Electric and motor patterns associated with canine jejunal transit of liquids and solids

B. W. Miedema, M. G. Sarr, R. B. Hanson, K. A. Kelly

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Our hypothesis was that the direction of liquid transit through the canine jejunum is determined by the direction that single jejunal pressure waves spread, while the direction of solid transit depends on the direction of spread of both single waves and clustered waves. In six dogs, 80-cm jejunal Vella loops were made and fitted with manometric catheters and serosal electrodes. After recovery, transit of liquids (Ringer lactate) and solids (2.4-mm nylon spheres) placed into the center of the loop was determined in the conscious animals while pacing the loop in a forward direction or in a backward direction. Under fasting and fed conditions, single pressure waves followed the direction of pacing, while the direction of migration of clustered waves was not determined by the direction of pacing. Liquid transit always followed the direction of single pressure waves. In contrast, solids moved distally regardless of the direction of pacing, except when liquids were also present in the lumen, in which case solids moved in the same direction as the single pressure waves.

Original languageEnglish (US)
Pages (from-to)G962-G970
JournalAmerican Journal of Physiology - Gastrointestinal and Liver Physiology
Volume262
Issue number6 25-6
DOIs
StatePublished - 1992

Keywords

  • computer analysis
  • contractile activity
  • interdigestive motility
  • intestinal pacing
  • jejunal motility
  • motility
  • myoelectric activity
  • postprandial motility

ASJC Scopus subject areas

  • Physiology
  • Hepatology
  • Gastroenterology
  • Physiology (medical)

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