Efficient delivery of gold nanoparticles by dual receptor targeting

Sanjib Bhattacharyya, Jameel Ahmad Khan, Geoffry L. Curran, J. David Robertson, Resham Bhattacharya, Priyabrata Mukherjee

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

The fabrication and characterization of a dual receptor targeted system (DRTS) are described. It is demonstrated that DRTS is more efficient at delivering gold nanoparticles (AuNPs) to ovarian cancer cells expressing epidermal growth factor receptor (EGFR) and folate receptor (FR) than their corresponding single-receptor-targeting systems (SRTS).

Original languageEnglish (US)
Pages (from-to)5034-5038
Number of pages5
JournalAdvanced Materials
Volume23
Issue number43
DOIs
StatePublished - Nov 16 2011

Keywords

  • biomedical applications
  • epidermal growth factor receptors (EGFR)
  • folate receptors (FR)
  • gold nanoparticles

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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  • Cite this

    Bhattacharyya, S., Khan, J. A., Curran, G. L., Robertson, J. D., Bhattacharya, R., & Mukherjee, P. (2011). Efficient delivery of gold nanoparticles by dual receptor targeting. Advanced Materials, 23(43), 5034-5038. https://doi.org/10.1002/adma.201102287