Efficient delivery of gold nanoparticles by dual receptor targeting

Sanjib Bhattacharyya, Jameel Ahmad Khan, Geoffry L. Curran, J. David Robertson, Resham Bhattacharya, Priyabrata Mukherjee

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

The fabrication and characterization of a dual receptor targeted system (DRTS) are described. It is demonstrated that DRTS is more efficient at delivering gold nanoparticles (AuNPs) to ovarian cancer cells expressing epidermal growth factor receptor (EGFR) and folate receptor (FR) than their corresponding single-receptor-targeting systems (SRTS).

Original languageEnglish (US)
Pages (from-to)5034-5038
Number of pages5
JournalAdvanced Materials
Volume23
Issue number43
DOIs
StatePublished - Nov 16 2011

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Folic Acid
Epidermal Growth Factor Receptor
Gold
Cells
Nanoparticles
Fabrication
Epidermal Growth Factor

Keywords

  • biomedical applications
  • epidermal growth factor receptors (EGFR)
  • folate receptors (FR)
  • gold nanoparticles

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Bhattacharyya, S., Khan, J. A., Curran, G. L., Robertson, J. D., Bhattacharya, R., & Mukherjee, P. (2011). Efficient delivery of gold nanoparticles by dual receptor targeting. Advanced Materials, 23(43), 5034-5038. https://doi.org/10.1002/adma.201102287

Efficient delivery of gold nanoparticles by dual receptor targeting. / Bhattacharyya, Sanjib; Khan, Jameel Ahmad; Curran, Geoffry L.; Robertson, J. David; Bhattacharya, Resham; Mukherjee, Priyabrata.

In: Advanced Materials, Vol. 23, No. 43, 16.11.2011, p. 5034-5038.

Research output: Contribution to journalArticle

Bhattacharyya, S, Khan, JA, Curran, GL, Robertson, JD, Bhattacharya, R & Mukherjee, P 2011, 'Efficient delivery of gold nanoparticles by dual receptor targeting', Advanced Materials, vol. 23, no. 43, pp. 5034-5038. https://doi.org/10.1002/adma.201102287
Bhattacharyya S, Khan JA, Curran GL, Robertson JD, Bhattacharya R, Mukherjee P. Efficient delivery of gold nanoparticles by dual receptor targeting. Advanced Materials. 2011 Nov 16;23(43):5034-5038. https://doi.org/10.1002/adma.201102287
Bhattacharyya, Sanjib ; Khan, Jameel Ahmad ; Curran, Geoffry L. ; Robertson, J. David ; Bhattacharya, Resham ; Mukherjee, Priyabrata. / Efficient delivery of gold nanoparticles by dual receptor targeting. In: Advanced Materials. 2011 ; Vol. 23, No. 43. pp. 5034-5038.
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