Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease

Ryan J. Uitti, Robert E. Wharen, Margaret F. Turk

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We evaluated motor function in 41 consecutive PD patients undergoing unilateral MRI/microelectrode-guided posteroventral pallidotomy to determine whether the motor effects of levodopa therapy change after surgery. Total Unified Parkinson's Disease Rating Scale motor 'off' and motor 'on' subscores all improved and the rapidity of action, magnitude, and duration of motor response to levodopa therapy were all maintained after pallidotomy.

Original languageEnglish (US)
Pages (from-to)1755-1757
Number of pages3
JournalNeurology
Volume51
Issue number6
StatePublished - Dec 1998

Fingerprint

Pallidotomy
Levodopa
Parkinson Disease
Microelectrodes
Therapeutics

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease. / Uitti, Ryan J.; Wharen, Robert E.; Turk, Margaret F.

In: Neurology, Vol. 51, No. 6, 12.1998, p. 1755-1757.

Research output: Contribution to journalArticle

Uitti, RJ, Wharen, RE & Turk, MF 1998, 'Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease', Neurology, vol. 51, no. 6, pp. 1755-1757.
Uitti, Ryan J. ; Wharen, Robert E. ; Turk, Margaret F. / Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease. In: Neurology. 1998 ; Vol. 51, No. 6. pp. 1755-1757.
@article{3bc9790ec40f40418f957a7a30d4c89e,
title = "Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease",
abstract = "We evaluated motor function in 41 consecutive PD patients undergoing unilateral MRI/microelectrode-guided posteroventral pallidotomy to determine whether the motor effects of levodopa therapy change after surgery. Total Unified Parkinson's Disease Rating Scale motor 'off' and motor 'on' subscores all improved and the rapidity of action, magnitude, and duration of motor response to levodopa therapy were all maintained after pallidotomy.",
author = "Uitti, {Ryan J.} and Wharen, {Robert E.} and Turk, {Margaret F.}",
year = "1998",
month = "12",
language = "English (US)",
volume = "51",
pages = "1755--1757",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Efficacy of levodopa therapy on motor function after posteroventral pallidotomy for Parkinson's disease

AU - Uitti, Ryan J.

AU - Wharen, Robert E.

AU - Turk, Margaret F.

PY - 1998/12

Y1 - 1998/12

N2 - We evaluated motor function in 41 consecutive PD patients undergoing unilateral MRI/microelectrode-guided posteroventral pallidotomy to determine whether the motor effects of levodopa therapy change after surgery. Total Unified Parkinson's Disease Rating Scale motor 'off' and motor 'on' subscores all improved and the rapidity of action, magnitude, and duration of motor response to levodopa therapy were all maintained after pallidotomy.

AB - We evaluated motor function in 41 consecutive PD patients undergoing unilateral MRI/microelectrode-guided posteroventral pallidotomy to determine whether the motor effects of levodopa therapy change after surgery. Total Unified Parkinson's Disease Rating Scale motor 'off' and motor 'on' subscores all improved and the rapidity of action, magnitude, and duration of motor response to levodopa therapy were all maintained after pallidotomy.

UR - http://www.scopus.com/inward/record.url?scp=0031648843&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031648843&partnerID=8YFLogxK

M3 - Article

C2 - 9855542

AN - SCOPUS:0031648843

VL - 51

SP - 1755

EP - 1757

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 6

ER -