Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling

Pedro F. Monteiro; Steve R. Ommen; Bernard J. Gersh; Joseph A. Dearani; Hartzell V. Schaff; Rick A. Nishimura; A. Jamil Tajik

doi:10.1016/j.amjcard.2007.07.031

Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling

Pedro F. Monteiro, Steve R. Ommen, Bernard J. Gersh, Joseph A. Dearani, Hartzell V. Schaff, Rick A. Nishimura, A. Jamil Tajik

Cardiovascular Surgery

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

This study was conducted to examine the late effects of surgical myectomy on left ventricular (LV) structure and diastolic function in patients with obstructive hypertrophic cardiomyopathy. Patients with hypertrophic cardiomyopathy who had complete echocardiographic studies before and ≥6 months after myectomy were included in this retrospective analysis of cavity dimension, septal and LV posterior wall thicknesses, and Doppler flow variables. Compared with preoperative measurement, mean septal thickness (23.6 vs 19.5 mm, p <0.001) and LV posterior wall thickness (14.2 vs 12.4 mm, p <0.001) were smaller after myectomy. Likewise, mitral inflow Doppler velocity curves indicated improvement in LV filling, with decreased mitral E velocity (0.95 to 0.87 m/s, p = 0.008). In conclusion, the long-term benefits of this operation may be mediated in part by favorable LV remodeling and changes in LV diastolic filling.

Original language	English (US)
Pages (from-to)	1776-1778
Number of pages	3
Journal	American Journal of Cardiology
Volume	100
Issue number	12
DOIs	https://doi.org/10.1016/j.amjcard.2007.07.031
State	Published - Dec 15 2007

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.amjcard.2007.07.031

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title = "Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling",

abstract = "This study was conducted to examine the late effects of surgical myectomy on left ventricular (LV) structure and diastolic function in patients with obstructive hypertrophic cardiomyopathy. Patients with hypertrophic cardiomyopathy who had complete echocardiographic studies before and ≥6 months after myectomy were included in this retrospective analysis of cavity dimension, septal and LV posterior wall thicknesses, and Doppler flow variables. Compared with preoperative measurement, mean septal thickness (23.6 vs 19.5 mm, p <0.001) and LV posterior wall thickness (14.2 vs 12.4 mm, p <0.001) were smaller after myectomy. Likewise, mitral inflow Doppler velocity curves indicated improvement in LV filling, with decreased mitral E velocity (0.95 to 0.87 m/s, p = 0.008). In conclusion, the long-term benefits of this operation may be mediated in part by favorable LV remodeling and changes in LV diastolic filling.",

author = "Monteiro, {Pedro F.} and Ommen, {Steve R.} and Gersh, {Bernard J.} and Dearani, {Joseph A.} and Schaff, {Hartzell V.} and Nishimura, {Rick A.} and Tajik, {A. Jamil}",

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T1 - Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling

AU - Monteiro, Pedro F.

AU - Ommen, Steve R.

AU - Gersh, Bernard J.

AU - Dearani, Joseph A.

AU - Schaff, Hartzell V.

AU - Nishimura, Rick A.

AU - Tajik, A. Jamil

PY - 2007/12/15

Y1 - 2007/12/15

N2 - This study was conducted to examine the late effects of surgical myectomy on left ventricular (LV) structure and diastolic function in patients with obstructive hypertrophic cardiomyopathy. Patients with hypertrophic cardiomyopathy who had complete echocardiographic studies before and ≥6 months after myectomy were included in this retrospective analysis of cavity dimension, septal and LV posterior wall thicknesses, and Doppler flow variables. Compared with preoperative measurement, mean septal thickness (23.6 vs 19.5 mm, p <0.001) and LV posterior wall thickness (14.2 vs 12.4 mm, p <0.001) were smaller after myectomy. Likewise, mitral inflow Doppler velocity curves indicated improvement in LV filling, with decreased mitral E velocity (0.95 to 0.87 m/s, p = 0.008). In conclusion, the long-term benefits of this operation may be mediated in part by favorable LV remodeling and changes in LV diastolic filling.

AB - This study was conducted to examine the late effects of surgical myectomy on left ventricular (LV) structure and diastolic function in patients with obstructive hypertrophic cardiomyopathy. Patients with hypertrophic cardiomyopathy who had complete echocardiographic studies before and ≥6 months after myectomy were included in this retrospective analysis of cavity dimension, septal and LV posterior wall thicknesses, and Doppler flow variables. Compared with preoperative measurement, mean septal thickness (23.6 vs 19.5 mm, p <0.001) and LV posterior wall thickness (14.2 vs 12.4 mm, p <0.001) were smaller after myectomy. Likewise, mitral inflow Doppler velocity curves indicated improvement in LV filling, with decreased mitral E velocity (0.95 to 0.87 m/s, p = 0.008). In conclusion, the long-term benefits of this operation may be mediated in part by favorable LV remodeling and changes in LV diastolic filling.

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ER -

Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling

Abstract

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