Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling

Pedro F. Monteiro, Steve R. Ommen, Bernard J. Gersh, Joseph A. Dearani, Hartzell V Schaff, Rick A. Nishimura, A. Jamil Tajik

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

This study was conducted to examine the late effects of surgical myectomy on left ventricular (LV) structure and diastolic function in patients with obstructive hypertrophic cardiomyopathy. Patients with hypertrophic cardiomyopathy who had complete echocardiographic studies before and ≥6 months after myectomy were included in this retrospective analysis of cavity dimension, septal and LV posterior wall thicknesses, and Doppler flow variables. Compared with preoperative measurement, mean septal thickness (23.6 vs 19.5 mm, p <0.001) and LV posterior wall thickness (14.2 vs 12.4 mm, p <0.001) were smaller after myectomy. Likewise, mitral inflow Doppler velocity curves indicated improvement in LV filling, with decreased mitral E velocity (0.95 to 0.87 m/s, p = 0.008). In conclusion, the long-term benefits of this operation may be mediated in part by favorable LV remodeling and changes in LV diastolic filling.

Original languageEnglish (US)
Pages (from-to)1776-1778
Number of pages3
JournalAmerican Journal of Cardiology
Volume100
Issue number12
DOIs
StatePublished - Dec 15 2007

Fingerprint

Hypertrophic Cardiomyopathy
Ventricular Remodeling

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Monteiro, P. F., Ommen, S. R., Gersh, B. J., Dearani, J. A., Schaff, H. V., Nishimura, R. A., & Tajik, A. J. (2007). Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling. American Journal of Cardiology, 100(12), 1776-1778. https://doi.org/10.1016/j.amjcard.2007.07.031

Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling. / Monteiro, Pedro F.; Ommen, Steve R.; Gersh, Bernard J.; Dearani, Joseph A.; Schaff, Hartzell V; Nishimura, Rick A.; Tajik, A. Jamil.

In: American Journal of Cardiology, Vol. 100, No. 12, 15.12.2007, p. 1776-1778.

Research output: Contribution to journalArticle

Monteiro, PF, Ommen, SR, Gersh, BJ, Dearani, JA, Schaff, HV, Nishimura, RA & Tajik, AJ 2007, 'Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling', American Journal of Cardiology, vol. 100, no. 12, pp. 1776-1778. https://doi.org/10.1016/j.amjcard.2007.07.031
Monteiro, Pedro F. ; Ommen, Steve R. ; Gersh, Bernard J. ; Dearani, Joseph A. ; Schaff, Hartzell V ; Nishimura, Rick A. ; Tajik, A. Jamil. / Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling. In: American Journal of Cardiology. 2007 ; Vol. 100, No. 12. pp. 1776-1778.
@article{bce66dfbd34a4543b27921d870504f51,
title = "Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling",
abstract = "This study was conducted to examine the late effects of surgical myectomy on left ventricular (LV) structure and diastolic function in patients with obstructive hypertrophic cardiomyopathy. Patients with hypertrophic cardiomyopathy who had complete echocardiographic studies before and ≥6 months after myectomy were included in this retrospective analysis of cavity dimension, septal and LV posterior wall thicknesses, and Doppler flow variables. Compared with preoperative measurement, mean septal thickness (23.6 vs 19.5 mm, p <0.001) and LV posterior wall thickness (14.2 vs 12.4 mm, p <0.001) were smaller after myectomy. Likewise, mitral inflow Doppler velocity curves indicated improvement in LV filling, with decreased mitral E velocity (0.95 to 0.87 m/s, p = 0.008). In conclusion, the long-term benefits of this operation may be mediated in part by favorable LV remodeling and changes in LV diastolic filling.",
author = "Monteiro, {Pedro F.} and Ommen, {Steve R.} and Gersh, {Bernard J.} and Dearani, {Joseph A.} and Schaff, {Hartzell V} and Nishimura, {Rick A.} and Tajik, {A. Jamil}",
year = "2007",
month = "12",
day = "15",
doi = "10.1016/j.amjcard.2007.07.031",
language = "English (US)",
volume = "100",
pages = "1776--1778",
journal = "American Journal of Cardiology",
issn = "0002-9149",
publisher = "Elsevier Inc.",
number = "12",

}

TY - JOUR

T1 - Effects of Surgical Septal Myectomy on Left Ventricular Wall Thickness and Diastolic Filling

AU - Monteiro, Pedro F.

AU - Ommen, Steve R.

AU - Gersh, Bernard J.

AU - Dearani, Joseph A.

AU - Schaff, Hartzell V

AU - Nishimura, Rick A.

AU - Tajik, A. Jamil

PY - 2007/12/15

Y1 - 2007/12/15

N2 - This study was conducted to examine the late effects of surgical myectomy on left ventricular (LV) structure and diastolic function in patients with obstructive hypertrophic cardiomyopathy. Patients with hypertrophic cardiomyopathy who had complete echocardiographic studies before and ≥6 months after myectomy were included in this retrospective analysis of cavity dimension, septal and LV posterior wall thicknesses, and Doppler flow variables. Compared with preoperative measurement, mean septal thickness (23.6 vs 19.5 mm, p <0.001) and LV posterior wall thickness (14.2 vs 12.4 mm, p <0.001) were smaller after myectomy. Likewise, mitral inflow Doppler velocity curves indicated improvement in LV filling, with decreased mitral E velocity (0.95 to 0.87 m/s, p = 0.008). In conclusion, the long-term benefits of this operation may be mediated in part by favorable LV remodeling and changes in LV diastolic filling.

AB - This study was conducted to examine the late effects of surgical myectomy on left ventricular (LV) structure and diastolic function in patients with obstructive hypertrophic cardiomyopathy. Patients with hypertrophic cardiomyopathy who had complete echocardiographic studies before and ≥6 months after myectomy were included in this retrospective analysis of cavity dimension, septal and LV posterior wall thicknesses, and Doppler flow variables. Compared with preoperative measurement, mean septal thickness (23.6 vs 19.5 mm, p <0.001) and LV posterior wall thickness (14.2 vs 12.4 mm, p <0.001) were smaller after myectomy. Likewise, mitral inflow Doppler velocity curves indicated improvement in LV filling, with decreased mitral E velocity (0.95 to 0.87 m/s, p = 0.008). In conclusion, the long-term benefits of this operation may be mediated in part by favorable LV remodeling and changes in LV diastolic filling.

UR - http://www.scopus.com/inward/record.url?scp=36849010864&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36849010864&partnerID=8YFLogxK

U2 - 10.1016/j.amjcard.2007.07.031

DO - 10.1016/j.amjcard.2007.07.031

M3 - Article

C2 - 18082525

AN - SCOPUS:36849010864

VL - 100

SP - 1776

EP - 1778

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 12

ER -