Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1: The Lung Health Study

Nicholas R. Anthonisen; John E. Connett; James P. Kiley; Murray D. Altose; William C. Bailey; A. Sonia Buist; William A. Conway; Paul L. Enright; Richard E. Kanner; Peggy O'hara; Gregory R. Owens; Paul D. Scanlon; Donald P. Tashkin; Robert A. Wise; M. D. Altose; A. F. Connors; S. Redline; C. Deitz; R. F. Rakos; W. A. Conway; A. Dehorn; J. C. Ward; C. S. Hoppe Ryan; R. L. Jentons; J. A. Reddick; C. Sawicki; R. A. Wise; S. Permutt; C. S. Rand; P. D. Scanlon; L. J. Davis; R. D. Hurt; R. D. Miller; D. E. Williams; G. M. Caron; G. G. Lauger; S. M. Toogood; A. S. Buist; W. M. Bjornson; L. R. Johnson; W. C. Bailey; C. M. Brooks; J. J. Dolce; D. M. Higgins; M. A. Johnson; C. D. Lorish; B. A. Martin; D. P. Tashkin; A. H. Coulson; H. Gong; P. I. Harber; V. C. Roth; M. Roth; M. A. Nides; M. S. Simmons; I. Zuniga; N. R. Anthonisen; J. Manfreda; R. P. Murray; S. C. Rempel Rossum; J. M. Stoyko; J. E. Connett; M. O. Kjelsberg; M. K. Cowles; D. A. Durkin; P. L. Enright; K. J. Kurnow; W. W. Lee; P. G. Lindgren; S. J. Mongin; P. O'hara; H. T. Voelker; L. A. Waller; G. R. Owens; R. M. Rogers; J. J. Johnston; F. P. Pope; F. M. Vitale; R. E. Kanner; M. A. Rigdon; K. C. Benton; P. M. Grant; M. Becklake; B. Burrows; P. Cleary; P. Kimbel; L. Nett; J. K. Ockene; R. M. Senior; G. L. Snider; W. Spitzer; O. D. Williams; S. S. Hurd; J. P. Kiley; M. C. Ayres; S. M. Ayres; R. E. Hyatt; B. A. Mason

doi:10.1001/jama.1994.03520190043033

Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1: The Lung Health Study

Nicholas R. Anthonisen, John E. Connett, James P. Kiley, Murray D. Altose, William C. Bailey, A. Sonia Buist, William A. Conway, Paul L. Enright, Richard E. Kanner, Peggy O'hara, Gregory R. Owens, Paul D. Scanlon, Donald P. Tashkin, Robert A. Wise, M. D. Altose, A. F. Connors, S. Redline, C. Deitz, R. F. Rakos, W. A. ConwayA. Dehorn, J. C. Ward, C. S. Hoppe Ryan, R. L. Jentons, J. A. Reddick, C. Sawicki, R. A. Wise, S. Permutt, C. S. Rand, P. D. Scanlon, L. J. Davis, R. D. Hurt, R. D. Miller, D. E. Williams, G. M. Caron, G. G. Lauger, S. M. Toogood, A. S. Buist, W. M. Bjornson, L. R. Johnson, W. C. Bailey, C. M. Brooks, J. J. Dolce, D. M. Higgins, M. A. Johnson, C. D. Lorish, B. A. Martin, D. P. Tashkin, A. H. Coulson, H. Gong, P. I. Harber, V. C. Roth, M. Roth, M. A. Nides, M. S. Simmons, I. Zuniga, N. R. Anthonisen, J. Manfreda, R. P. Murray, S. C. Rempel Rossum, J. M. Stoyko, J. E. Connett, M. O. Kjelsberg, M. K. Cowles, D. A. Durkin, P. L. Enright, K. J. Kurnow, W. W. Lee, P. G. Lindgren, S. J. Mongin, P. O'hara, H. T. Voelker, L. A. Waller, G. R. Owens, R. M. Rogers, J. J. Johnston, F. P. Pope, F. M. Vitale, R. E. Kanner, M. A. Rigdon, K. C. Benton, P. M. Grant, M. Becklake, B. Burrows, P. Cleary, P. Kimbel, L. Nett, J. K. Ockene, R. M. Senior, G. L. Snider, W. Spitzer, O. D. Williams, S. S. Hurd, J. P. Kiley, M. C. Ayres, S. M. Ayres, R. E. Hyatt, B. A. Mason

Research output: Contribution to journal › Article › peer-review

1656 Scopus citations

Original language	English (US)
Pages (from-to)	1497-1505
Number of pages	9
Journal	JAMA: The Journal of the American Medical Association
Volume	272
Issue number	19
DOIs	https://doi.org/10.1001/jama.1994.03520190043033
State	Published - Nov 1994

ASJC Scopus subject areas

Medicine(all)

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10.1001/jama.1994.03520190043033

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Anthonisen, N. R., Connett, J. E., Kiley, J. P., Altose, M. D., Bailey, W. C., Buist, A. S., Conway, W. A., Enright, P. L., Kanner, R. E., O'hara, P., Owens, G. R., Scanlon, P. D., Tashkin, D. P., Wise, R. A., Altose, M. D., Connors, A. F., Redline, S., Deitz, C., Rakos, R. F., ... Mason, B. A. (1994). Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1: The Lung Health Study. JAMA: The Journal of the American Medical Association, 272(19), 1497-1505. https://doi.org/10.1001/jama.1994.03520190043033

Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1 : The Lung Health Study. / Anthonisen, Nicholas R.; Connett, John E.; Kiley, James P.; Altose, Murray D.; Bailey, William C.; Buist, A. Sonia; Conway, William A.; Enright, Paul L.; Kanner, Richard E.; O'hara, Peggy; Owens, Gregory R.; Scanlon, Paul D.; Tashkin, Donald P.; Wise, Robert A.; Altose, M. D.; Connors, A. F.; Redline, S.; Deitz, C.; Rakos, R. F.; Conway, W. A.; Dehorn, A.; Ward, J. C.; Hoppe Ryan, C. S.; Jentons, R. L.; Reddick, J. A.; Sawicki, C.; Wise, R. A.; Permutt, S.; Rand, C. S.; Scanlon, P. D.; Davis, L. J.; Hurt, R. D.; Miller, R. D.; Williams, D. E.; Caron, G. M.; Lauger, G. G.; Toogood, S. M.; Buist, A. S.; Bjornson, W. M.; Johnson, L. R.; Bailey, W. C.; Brooks, C. M.; Dolce, J. J.; Higgins, D. M.; Johnson, M. A.; Lorish, C. D.; Martin, B. A.; Tashkin, D. P.; Coulson, A. H.; Gong, H.; Harber, P. I.; Roth, V. C.; Roth, M.; Nides, M. A.; Simmons, M. S.; Zuniga, I.; Anthonisen, N. R.; Manfreda, J.; Murray, R. P.; Rempel Rossum, S. C.; Stoyko, J. M.; Connett, J. E.; Kjelsberg, M. O.; Cowles, M. K.; Durkin, D. A.; Enright, P. L.; Kurnow, K. J.; Lee, W. W.; Lindgren, P. G.; Mongin, S. J.; O'hara, P.; Voelker, H. T.; Waller, L. A.; Owens, G. R.; Rogers, R. M.; Johnston, J. J.; Pope, F. P.; Vitale, F. M.; Kanner, R. E.; Rigdon, M. A.; Benton, K. C.; Grant, P. M.; Becklake, M.; Burrows, B.; Cleary, P.; Kimbel, P.; Nett, L.; Ockene, J. K.; Senior, R. M.; Snider, G. L.; Spitzer, W.; Williams, O. D.; Hurd, S. S.; Kiley, J. P.; Ayres, M. C.; Ayres, S. M.; Hyatt, R. E.; Mason, B. A.

In: JAMA: The Journal of the American Medical Association, Vol. 272, No. 19, 11.1994, p. 1497-1505.

Research output: Contribution to journal › Article › peer-review

Anthonisen, NR, Connett, JE, Kiley, JP, Altose, MD, Bailey, WC, Buist, AS, Conway, WA, Enright, PL, Kanner, RE, O'hara, P, Owens, GR, Scanlon, PD, Tashkin, DP, Wise, RA, Altose, MD, Connors, AF, Redline, S, Deitz, C, Rakos, RF, Conway, WA, Dehorn, A, Ward, JC, Hoppe Ryan, CS, Jentons, RL, Reddick, JA, Sawicki, C, Wise, RA, Permutt, S, Rand, CS, Scanlon, PD, Davis, LJ, Hurt, RD, Miller, RD, Williams, DE, Caron, GM, Lauger, GG, Toogood, SM, Buist, AS, Bjornson, WM, Johnson, LR, Bailey, WC, Brooks, CM, Dolce, JJ, Higgins, DM, Johnson, MA, Lorish, CD, Martin, BA, Tashkin, DP, Coulson, AH, Gong, H, Harber, PI, Roth, VC, Roth, M, Nides, MA, Simmons, MS, Zuniga, I, Anthonisen, NR, Manfreda, J, Murray, RP, Rempel Rossum, SC, Stoyko, JM, Connett, JE, Kjelsberg, MO, Cowles, MK, Durkin, DA, Enright, PL, Kurnow, KJ, Lee, WW, Lindgren, PG, Mongin, SJ, O'hara, P, Voelker, HT, Waller, LA, Owens, GR, Rogers, RM, Johnston, JJ, Pope, FP, Vitale, FM, Kanner, RE, Rigdon, MA, Benton, KC, Grant, PM, Becklake, M, Burrows, B, Cleary, P, Kimbel, P, Nett, L, Ockene, JK, Senior, RM, Snider, GL, Spitzer, W, Williams, OD, Hurd, SS, Kiley, JP, Ayres, MC, Ayres, SM, Hyatt, RE & Mason, BA 1994, 'Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1: The Lung Health Study', JAMA: The Journal of the American Medical Association, vol. 272, no. 19, pp. 1497-1505. https://doi.org/10.1001/jama.1994.03520190043033

Anthonisen, Nicholas R. ; Connett, John E. ; Kiley, James P. ; Altose, Murray D. ; Bailey, William C. ; Buist, A. Sonia ; Conway, William A. ; Enright, Paul L. ; Kanner, Richard E. ; O'hara, Peggy ; Owens, Gregory R. ; Scanlon, Paul D. ; Tashkin, Donald P. ; Wise, Robert A. ; Altose, M. D. ; Connors, A. F. ; Redline, S. ; Deitz, C. ; Rakos, R. F. ; Conway, W. A. ; Dehorn, A. ; Ward, J. C. ; Hoppe Ryan, C. S. ; Jentons, R. L. ; Reddick, J. A. ; Sawicki, C. ; Wise, R. A. ; Permutt, S. ; Rand, C. S. ; Scanlon, P. D. ; Davis, L. J. ; Hurt, R. D. ; Miller, R. D. ; Williams, D. E. ; Caron, G. M. ; Lauger, G. G. ; Toogood, S. M. ; Buist, A. S. ; Bjornson, W. M. ; Johnson, L. R. ; Bailey, W. C. ; Brooks, C. M. ; Dolce, J. J. ; Higgins, D. M. ; Johnson, M. A. ; Lorish, C. D. ; Martin, B. A. ; Tashkin, D. P. ; Coulson, A. H. ; Gong, H. ; Harber, P. I. ; Roth, V. C. ; Roth, M. ; Nides, M. A. ; Simmons, M. S. ; Zuniga, I. ; Anthonisen, N. R. ; Manfreda, J. ; Murray, R. P. ; Rempel Rossum, S. C. ; Stoyko, J. M. ; Connett, J. E. ; Kjelsberg, M. O. ; Cowles, M. K. ; Durkin, D. A. ; Enright, P. L. ; Kurnow, K. J. ; Lee, W. W. ; Lindgren, P. G. ; Mongin, S. J. ; O'hara, P. ; Voelker, H. T. ; Waller, L. A. ; Owens, G. R. ; Rogers, R. M. ; Johnston, J. J. ; Pope, F. P. ; Vitale, F. M. ; Kanner, R. E. ; Rigdon, M. A. ; Benton, K. C. ; Grant, P. M. ; Becklake, M. ; Burrows, B. ; Cleary, P. ; Kimbel, P. ; Nett, L. ; Ockene, J. K. ; Senior, R. M. ; Snider, G. L. ; Spitzer, W. ; Williams, O. D. ; Hurd, S. S. ; Kiley, J. P. ; Ayres, M. C. ; Ayres, S. M. ; Hyatt, R. E. ; Mason, B. A. / Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1 : The Lung Health Study. In: JAMA: The Journal of the American Medical Association. 1994 ; Vol. 272, No. 19. pp. 1497-1505.

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title = "Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1: The Lung Health Study",

author = "Anthonisen, {Nicholas R.} and Connett, {John E.} and Kiley, {James P.} and Altose, {Murray D.} and Bailey, {William C.} and Buist, {A. Sonia} and Conway, {William A.} and Enright, {Paul L.} and Kanner, {Richard E.} and Peggy O'hara and Owens, {Gregory R.} and Scanlon, {Paul D.} and Tashkin, {Donald P.} and Wise, {Robert A.} and Altose, {M. D.} and Connors, {A. F.} and S. Redline and C. Deitz and Rakos, {R. F.} and Conway, {W. A.} and A. Dehorn and Ward, {J. C.} and {Hoppe Ryan}, {C. S.} and Jentons, {R. L.} and Reddick, {J. A.} and C. Sawicki and Wise, {R. A.} and S. Permutt and Rand, {C. S.} and Scanlon, {P. D.} and Davis, {L. J.} and Hurt, {R. D.} and Miller, {R. D.} and Williams, {D. E.} and Caron, {G. M.} and Lauger, {G. G.} and Toogood, {S. M.} and Buist, {A. S.} and Bjornson, {W. M.} and Johnson, {L. R.} and Bailey, {W. C.} and Brooks, {C. M.} and Dolce, {J. J.} and Higgins, {D. M.} and Johnson, {M. A.} and Lorish, {C. D.} and Martin, {B. A.} and Tashkin, {D. P.} and Coulson, {A. H.} and H. Gong and Harber, {P. I.} and Roth, {V. C.} and M. Roth and Nides, {M. A.} and Simmons, {M. S.} and I. Zuniga and Anthonisen, {N. R.} and J. Manfreda and Murray, {R. P.} and {Rempel Rossum}, {S. C.} and Stoyko, {J. M.} and Connett, {J. E.} and Kjelsberg, {M. O.} and Cowles, {M. K.} and Durkin, {D. A.} and Enright, {P. L.} and Kurnow, {K. J.} and Lee, {W. W.} and Lindgren, {P. G.} and Mongin, {S. J.} and P. O'hara and Voelker, {H. T.} and Waller, {L. A.} and Owens, {G. R.} and Rogers, {R. M.} and Johnston, {J. J.} and Pope, {F. P.} and Vitale, {F. M.} and Kanner, {R. E.} and Rigdon, {M. A.} and Benton, {K. C.} and Grant, {P. M.} and M. Becklake and B. Burrows and P. Cleary and P. Kimbel and L. Nett and Ockene, {J. K.} and Senior, {R. M.} and Snider, {G. L.} and W. Spitzer and Williams, {O. D.} and Hurd, {S. S.} and Kiley, {J. P.} and Ayres, {M. C.} and Ayres, {S. M.} and Hyatt, {R. E.} and Mason, {B. A.}",

note = "Funding Information: ThisstudywassupportedbycontractN01-HR- 46002fromtheDivisionofLungDiseasesofthe NationalHeart,Lung,andBloodInstitute.The SaltLakeCityCenterhasbeenassistedbythe ClinicalResearchCenter,PublicHealthResearch grant M01-RR00064 from the National Center for ResearchResources. Thefollowingpharmaceuticalcompaniessup¬ plieddrugsusedinthisstudy:BoehringerIngel- heimPharmaceuticalsIne,Ridgefield,Conn(Atro- vent andplaceboinhalers);MarionMerrellDow Ine,KansasCity,Mo(Nicorette,2mg).",

year = "1994",

month = nov,

doi = "10.1001/jama.1994.03520190043033",

language = "English (US)",

volume = "272",

pages = "1497--1505",

journal = "JAMA - Journal of the American Medical Association",

issn = "0002-9955",

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number = "19",

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TY - JOUR

T1 - Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1

T2 - The Lung Health Study

AU - Anthonisen, Nicholas R.

AU - Connett, John E.

AU - Kiley, James P.

AU - Altose, Murray D.

AU - Bailey, William C.

AU - Buist, A. Sonia

AU - Conway, William A.

AU - Enright, Paul L.

AU - Kanner, Richard E.

AU - O'hara, Peggy

AU - Owens, Gregory R.

AU - Scanlon, Paul D.

AU - Tashkin, Donald P.

AU - Wise, Robert A.

AU - Altose, M. D.

AU - Connors, A. F.

AU - Redline, S.

AU - Deitz, C.

AU - Rakos, R. F.

AU - Conway, W. A.

AU - Dehorn, A.

AU - Ward, J. C.

AU - Hoppe Ryan, C. S.

AU - Jentons, R. L.

AU - Reddick, J. A.

AU - Sawicki, C.

AU - Wise, R. A.

AU - Permutt, S.

AU - Rand, C. S.

AU - Scanlon, P. D.

AU - Davis, L. J.

AU - Hurt, R. D.

AU - Miller, R. D.

AU - Williams, D. E.

AU - Caron, G. M.

AU - Lauger, G. G.

AU - Toogood, S. M.

AU - Buist, A. S.

AU - Bjornson, W. M.

AU - Johnson, L. R.

AU - Bailey, W. C.

AU - Brooks, C. M.

AU - Dolce, J. J.

AU - Higgins, D. M.

AU - Johnson, M. A.

AU - Lorish, C. D.

AU - Martin, B. A.

AU - Tashkin, D. P.

AU - Coulson, A. H.

AU - Gong, H.

AU - Harber, P. I.

AU - Roth, V. C.

AU - Roth, M.

AU - Nides, M. A.

AU - Simmons, M. S.

AU - Zuniga, I.

AU - Anthonisen, N. R.

AU - Manfreda, J.

AU - Murray, R. P.

AU - Rempel Rossum, S. C.

AU - Stoyko, J. M.

AU - Connett, J. E.

AU - Kjelsberg, M. O.

AU - Cowles, M. K.

AU - Durkin, D. A.

AU - Enright, P. L.

AU - Kurnow, K. J.

AU - Lee, W. W.

AU - Lindgren, P. G.

AU - Mongin, S. J.

AU - O'hara, P.

AU - Voelker, H. T.

AU - Waller, L. A.

AU - Owens, G. R.

AU - Rogers, R. M.

AU - Johnston, J. J.

AU - Pope, F. P.

AU - Vitale, F. M.

AU - Kanner, R. E.

AU - Rigdon, M. A.

AU - Benton, K. C.

AU - Grant, P. M.

AU - Becklake, M.

AU - Burrows, B.

AU - Cleary, P.

AU - Kimbel, P.

AU - Nett, L.

AU - Ockene, J. K.

AU - Senior, R. M.

AU - Snider, G. L.

AU - Spitzer, W.

AU - Williams, O. D.

AU - Hurd, S. S.

AU - Kiley, J. P.

AU - Ayres, M. C.

AU - Ayres, S. M.

AU - Hyatt, R. E.

AU - Mason, B. A.

N1 - Funding Information: ThisstudywassupportedbycontractN01-HR- 46002fromtheDivisionofLungDiseasesofthe NationalHeart,Lung,andBloodInstitute.The SaltLakeCityCenterhasbeenassistedbythe ClinicalResearchCenter,PublicHealthResearch grant M01-RR00064 from the National Center for ResearchResources. Thefollowingpharmaceuticalcompaniessup¬ plieddrugsusedinthisstudy:BoehringerIngel- heimPharmaceuticalsIne,Ridgefield,Conn(Atro- vent andplaceboinhalers);MarionMerrellDow Ine,KansasCity,Mo(Nicorette,2mg).

PY - 1994/11

Y1 - 1994/11

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Effects of Smoking Intervention and the Use of an Inhaled Anticholinergic Bronchodilator on the Rate of Decline of FEV1: The Lung Health Study

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