Effects of Parental Opioid Use: Outcomes of Children of Parents in Medication-Assisted Treatment Compared to Healthy Controls

Hannah K. Betcher, Jennifer L. Vande Voort, Paul E. Croarkin, Kriti D. Gandhi, Julia Shekunov, Beth R. Larrabee, Mara G. Limbeck, Teresa A. Rummans, Magdalena Romanowicz

Research output: Contribution to journalArticle

Abstract

Background: Opioid use is a significant national crisis impacting individuals struggling with addiction and their families. The majority of individuals who abuse opioids are of child-rearing age, and critical knowledge gaps remain regarding how this abuse impacts their offspring. Fortunately, treatment for opioid use disorders is available. The primary goal of this study was to evaluate both physical and psychiatric diagnoses of children who have at least 1 parent participating in a buprenorphine-assisted treatment program. Methods: This retrospective study is based on chart review (January 1, 2010, through June 30, 2018). Children with parents receiving care in a buprenorphine clinic were identified and matched on sex, race, and age in a ratio of 1:5 with controls from the general pediatric clinic population. Data related to health outcomes were extracted from the medical records. Results: Compared to controls (n = 120), children of parents receiving buprenorphine-assisted treatment (n = 24) were more likely to have been born premature (odds ratio [OR] = 3.3, P = .035), had jaundice after birth (OR = 2.7, P = .034), had enuresis/encopresis (P < .001), and had been the victims of abuse or neglect (OR = 19.7, P = .0005). Children of parents with opioid use disorders were also more likely to utilize emergency services (ie, being seen in the emergency department for fussiness; OR = 4.0, P = .046) and were less likely to be covered by private insurance compared to state-funded insurance (OR = 0.2, P = .0013). Conclusions: Parental opioid use disorder impacts children. More research is needed to better describe long-term effects of treatment of parental opioid use on their offspring and to help design addiction treatment programs to support whole family units.

Original languageEnglish (US)
JournalThe primary care companion for CNS disorders
Volume21
Issue number4
DOIs
StatePublished - Aug 15 2019

Fingerprint

Opioid Analgesics
Parents
Buprenorphine
Odds Ratio
Insurance
Therapeutics
Encopresis
Child Rearing
Enuresis
Jaundice
Mental Disorders
Medical Records
Hospital Emergency Service
Emergencies
Retrospective Studies
Parturition
Pediatrics
Health
Research
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Effects of Parental Opioid Use : Outcomes of Children of Parents in Medication-Assisted Treatment Compared to Healthy Controls. / Betcher, Hannah K.; Vande Voort, Jennifer L.; Croarkin, Paul E.; Gandhi, Kriti D.; Shekunov, Julia; Larrabee, Beth R.; Limbeck, Mara G.; Rummans, Teresa A.; Romanowicz, Magdalena.

In: The primary care companion for CNS disorders, Vol. 21, No. 4, 15.08.2019.

Research output: Contribution to journalArticle

Betcher, Hannah K. ; Vande Voort, Jennifer L. ; Croarkin, Paul E. ; Gandhi, Kriti D. ; Shekunov, Julia ; Larrabee, Beth R. ; Limbeck, Mara G. ; Rummans, Teresa A. ; Romanowicz, Magdalena. / Effects of Parental Opioid Use : Outcomes of Children of Parents in Medication-Assisted Treatment Compared to Healthy Controls. In: The primary care companion for CNS disorders. 2019 ; Vol. 21, No. 4.
@article{09bea8e7b48741548bfc3d70370d5ed9,
title = "Effects of Parental Opioid Use: Outcomes of Children of Parents in Medication-Assisted Treatment Compared to Healthy Controls",
abstract = "Background: Opioid use is a significant national crisis impacting individuals struggling with addiction and their families. The majority of individuals who abuse opioids are of child-rearing age, and critical knowledge gaps remain regarding how this abuse impacts their offspring. Fortunately, treatment for opioid use disorders is available. The primary goal of this study was to evaluate both physical and psychiatric diagnoses of children who have at least 1 parent participating in a buprenorphine-assisted treatment program. Methods: This retrospective study is based on chart review (January 1, 2010, through June 30, 2018). Children with parents receiving care in a buprenorphine clinic were identified and matched on sex, race, and age in a ratio of 1:5 with controls from the general pediatric clinic population. Data related to health outcomes were extracted from the medical records. Results: Compared to controls (n = 120), children of parents receiving buprenorphine-assisted treatment (n = 24) were more likely to have been born premature (odds ratio [OR] = 3.3, P = .035), had jaundice after birth (OR = 2.7, P = .034), had enuresis/encopresis (P < .001), and had been the victims of abuse or neglect (OR = 19.7, P = .0005). Children of parents with opioid use disorders were also more likely to utilize emergency services (ie, being seen in the emergency department for fussiness; OR = 4.0, P = .046) and were less likely to be covered by private insurance compared to state-funded insurance (OR = 0.2, P = .0013). Conclusions: Parental opioid use disorder impacts children. More research is needed to better describe long-term effects of treatment of parental opioid use on their offspring and to help design addiction treatment programs to support whole family units.",
author = "Betcher, {Hannah K.} and {Vande Voort}, {Jennifer L.} and Croarkin, {Paul E.} and Gandhi, {Kriti D.} and Julia Shekunov and Larrabee, {Beth R.} and Limbeck, {Mara G.} and Rummans, {Teresa A.} and Magdalena Romanowicz",
year = "2019",
month = "8",
day = "15",
doi = "10.4088/PCC.19m02474",
language = "English (US)",
volume = "21",
journal = "The primary care companion for CNS disorders",
issn = "1523-5998",
publisher = "Physicians Postgraduate Press Inc.",
number = "4",

}

TY - JOUR

T1 - Effects of Parental Opioid Use

T2 - Outcomes of Children of Parents in Medication-Assisted Treatment Compared to Healthy Controls

AU - Betcher, Hannah K.

AU - Vande Voort, Jennifer L.

AU - Croarkin, Paul E.

AU - Gandhi, Kriti D.

AU - Shekunov, Julia

AU - Larrabee, Beth R.

AU - Limbeck, Mara G.

AU - Rummans, Teresa A.

AU - Romanowicz, Magdalena

PY - 2019/8/15

Y1 - 2019/8/15

N2 - Background: Opioid use is a significant national crisis impacting individuals struggling with addiction and their families. The majority of individuals who abuse opioids are of child-rearing age, and critical knowledge gaps remain regarding how this abuse impacts their offspring. Fortunately, treatment for opioid use disorders is available. The primary goal of this study was to evaluate both physical and psychiatric diagnoses of children who have at least 1 parent participating in a buprenorphine-assisted treatment program. Methods: This retrospective study is based on chart review (January 1, 2010, through June 30, 2018). Children with parents receiving care in a buprenorphine clinic were identified and matched on sex, race, and age in a ratio of 1:5 with controls from the general pediatric clinic population. Data related to health outcomes were extracted from the medical records. Results: Compared to controls (n = 120), children of parents receiving buprenorphine-assisted treatment (n = 24) were more likely to have been born premature (odds ratio [OR] = 3.3, P = .035), had jaundice after birth (OR = 2.7, P = .034), had enuresis/encopresis (P < .001), and had been the victims of abuse or neglect (OR = 19.7, P = .0005). Children of parents with opioid use disorders were also more likely to utilize emergency services (ie, being seen in the emergency department for fussiness; OR = 4.0, P = .046) and were less likely to be covered by private insurance compared to state-funded insurance (OR = 0.2, P = .0013). Conclusions: Parental opioid use disorder impacts children. More research is needed to better describe long-term effects of treatment of parental opioid use on their offspring and to help design addiction treatment programs to support whole family units.

AB - Background: Opioid use is a significant national crisis impacting individuals struggling with addiction and their families. The majority of individuals who abuse opioids are of child-rearing age, and critical knowledge gaps remain regarding how this abuse impacts their offspring. Fortunately, treatment for opioid use disorders is available. The primary goal of this study was to evaluate both physical and psychiatric diagnoses of children who have at least 1 parent participating in a buprenorphine-assisted treatment program. Methods: This retrospective study is based on chart review (January 1, 2010, through June 30, 2018). Children with parents receiving care in a buprenorphine clinic were identified and matched on sex, race, and age in a ratio of 1:5 with controls from the general pediatric clinic population. Data related to health outcomes were extracted from the medical records. Results: Compared to controls (n = 120), children of parents receiving buprenorphine-assisted treatment (n = 24) were more likely to have been born premature (odds ratio [OR] = 3.3, P = .035), had jaundice after birth (OR = 2.7, P = .034), had enuresis/encopresis (P < .001), and had been the victims of abuse or neglect (OR = 19.7, P = .0005). Children of parents with opioid use disorders were also more likely to utilize emergency services (ie, being seen in the emergency department for fussiness; OR = 4.0, P = .046) and were less likely to be covered by private insurance compared to state-funded insurance (OR = 0.2, P = .0013). Conclusions: Parental opioid use disorder impacts children. More research is needed to better describe long-term effects of treatment of parental opioid use on their offspring and to help design addiction treatment programs to support whole family units.

UR - http://www.scopus.com/inward/record.url?scp=85071581095&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071581095&partnerID=8YFLogxK

U2 - 10.4088/PCC.19m02474

DO - 10.4088/PCC.19m02474

M3 - Article

C2 - 31424700

AN - SCOPUS:85071581095

VL - 21

JO - The primary care companion for CNS disorders

JF - The primary care companion for CNS disorders

SN - 1523-5998

IS - 4

ER -