Effects of early handling upon puberty: Correlations with adrenal stress responsiveness

Gary Sieck, Judith A. Ramaley

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Handling of rat pups for 5 min once a week prior to weaning to permit weighing of the litter significantly delays vaginal opening and ovulation and is associated with a reduction in the response to an ether stress administered at 60 days of age. Handling combined with replacement of the bedding material results in a further delay in puberty and a further reduction in the stress response. It is therefore necessary to follow uniform handling procedures in any study of a developmental process.

Original languageEnglish (US)
Pages (from-to)487-489
Number of pages3
JournalPhysiology and Behavior
Volume15
Issue number4
DOIs
StatePublished - Oct 1975

Keywords

  • Adrenal
  • Handling
  • Maturation
  • Puberty
  • Stress

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

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