Effects of cerebrospinal fluid drainage in patients undergoing thoracic and thoracoabdominal aortic surgery

Michael J. Murray, Thomas C. Bower, William C. Oliver, Eric Werner, Peter Gloviczki

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Cerebrospinal fluid (CSF) drainage has been reported to protect the spinal cord during surgical procedures requiring thoracic aortic cross-clamping. In 1986, CSF pressure monitoring and drainage was begun in an attempt to reduce the incidence of paraplegia associated with surgical repair of descending thoracic and thoracoabdominal aortic aneurysms (TAAA). These Group II patients (n = 50) were retrospectively compared to Group I patients (n = 49) who had undergone similar surgical procedures in the previous 3 years before CSF monitoring was introduced into this practice. Group II patients had intrathecal catheters placed for monitoring of CSF pressure and drainage of CSF to maintain the pressure ≤15 mmHg. Seven patients (four in Group I, three in Group II) died before recovering from the anesthetic. Of the 47 patients in Group II who survived, none had clinically apparent complications such as an epidural hematoma or meningitis from the intrathecal catheter. The mean aortic cross-clamp time was 58.6 ± 30.5 minutes (mean ± SD) in Group I versus 65 ± 42.6 minutes in Group II. Twenty-three patients in Group I and 16 patients in Group II had a shunt to the distal aorta. To maintain a CSF pressure of ≤15 mmHg in Group II, an average of 46.9 ± 6.9 mL of CSF was withdrawn. Of the 45 survivors in Group I, 4 developed a spinal cord deficit; the number of patients with spinal cord deficit in Group II was 4 out of the 47 who survived. It was found that CSF drainage was relatively safe, but the study was unable to demonstrate improved neurologic outcome for patients undergoing repair of descending thoracic and TAAA.

Original languageEnglish (US)
Pages (from-to)266-272
Number of pages7
JournalJournal of Cardiothoracic and Vascular Anesthesia
Volume7
Issue number3
DOIs
StatePublished - 1993

Fingerprint

Thorax
Thoracic Aortic Aneurysm
Cerebrospinal Fluid Pressure
Cerebrospinal Fluid
Spinal Cord
Thoracic Surgical Procedures
Catheters
Cerebrospinal Fluid Leak
Paraplegia
Meningitis
Constriction
Hematoma
Nervous System
Survivors
Aorta
Anesthetics
Pressure
Incidence

Keywords

  • aortic surgery
  • neurologic ischemia
  • spinal cord paraplegia
  • thoracic aortic aneurysm

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Effects of cerebrospinal fluid drainage in patients undergoing thoracic and thoracoabdominal aortic surgery. / Murray, Michael J.; Bower, Thomas C.; Oliver, William C.; Werner, Eric; Gloviczki, Peter.

In: Journal of Cardiothoracic and Vascular Anesthesia, Vol. 7, No. 3, 1993, p. 266-272.

Research output: Contribution to journalArticle

Murray, Michael J. ; Bower, Thomas C. ; Oliver, William C. ; Werner, Eric ; Gloviczki, Peter. / Effects of cerebrospinal fluid drainage in patients undergoing thoracic and thoracoabdominal aortic surgery. In: Journal of Cardiothoracic and Vascular Anesthesia. 1993 ; Vol. 7, No. 3. pp. 266-272.
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