Effects of acute reperfusion on regional myocardial function: serial two-dimensional echocardiography assessment

Jae Kuen Oh, Bernard J. Gersh, Louis A. Nassef, Fletcher A Jr. Miller, James H. Chesebro, David Holmes, Hugh C. Smith, A. Jamil Tajik

Research output: Contribution to journalArticle

20 Scopus citations


Serial two-dimensional echocardiography was performed in 23 patients with acute myocardial infarction who received intravenous thrombolytic therapy to evaluate the effect of acute reperfusion on regional wall motion abnormalities. Regional wall motion abnormalities improved in 4 of the 14 patients (29%) with successful reperfusion and in 1 of the 9 (11%) without successful reperfusion. Improvement was evident on two-dimensional echocardiography as early as 24 h after successful reperfusion. In successfully reperfused patients, the main determinant of improvement in regional wall motion abnormalities was duration from the onset of chest pain to the time of reperfusion (3.3 vs. 6.3 h in successfully reperfused patients without recovery of regional wall motion abnormalities; P < 0.001).

Original languageEnglish (US)
Pages (from-to)161-168
Number of pages8
JournalInternational Journal of Cardiology
Issue number2
StatePublished - 1989



  • Acute myocardial infarction
  • Regional myocardial function
  • Reperfusion
  • Two-dimensional echocardiography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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