Effects of a multidisciplinary quality of life intervention on sleep quality in patients with advanced cancer receiving radiation therapy

Melanie T. Gentry, Pamela J. Atherton, Maria Lapid, Preetha Sharone Rosen, Simon Kung, Jarrett Richardson, Shezad K. Niazi, William V. Bobo, Matthew M. Clark, Teresa A. Rummans

Research output: Contribution to journalArticle

Abstract

ObjectivesSleep disturbances are prevalent in cancer patients, especially those with advanced disease. There are few published intervention studies that address sleep issues in advanced cancer patients during the course of treatment. This study assesses the impact of a multidisciplinary quality of life (QOL) intervention on subjective sleep difficulties in patients with advanced cancer.MethodThis randomized trial investigated the comparative effects of a multidisciplinary QOL intervention (n = 54) vs. standard care (n = 63) on sleep quality in patients with advanced cancer receiving radiation therapy as a secondary endpoint. The intervention group attended six intervention sessions, while the standard care group received informational material only. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS), administered at baseline and weeks 4 (post-intervention), 27, and 52.ResultsThe intervention group had a statistically significant improvement in the PSQI total score and two components of sleep quality and daytime dysfunction than the control group at week 4. At week 27, although both groups showed improvements in sleep measures from baseline, there were no statistically significant differences between groups in any of the PSQI total and component scores, or ESS. At week 52, the intervention group used less sleep medication than control patients compared to baseline (p = 0.04) and had a lower ESS score (7.6 vs. 9.3, p = 0.03).Significance of resultsA multidisciplinary intervention to improve QOL can also improve sleep quality of advanced cancer patients undergoing radiation therapy. Those patients who completed the intervention also reported the use of less sleep medication.

Original languageEnglish (US)
JournalPalliative and Supportive Care
DOIs
StateAccepted/In press - Jan 1 2019

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Sleep
Radiotherapy
Quality of Life
Neoplasms
Control Groups

Keywords

  • Palliative
  • Sedative and hypnotics
  • Sleep dysfunction
  • Well-being

ASJC Scopus subject areas

  • Nursing(all)
  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Effects of a multidisciplinary quality of life intervention on sleep quality in patients with advanced cancer receiving radiation therapy. / Gentry, Melanie T.; Atherton, Pamela J.; Lapid, Maria; Rosen, Preetha Sharone; Kung, Simon; Richardson, Jarrett; Niazi, Shezad K.; Bobo, William V.; Clark, Matthew M.; Rummans, Teresa A.

In: Palliative and Supportive Care, 01.01.2019.

Research output: Contribution to journalArticle

Gentry, Melanie T. ; Atherton, Pamela J. ; Lapid, Maria ; Rosen, Preetha Sharone ; Kung, Simon ; Richardson, Jarrett ; Niazi, Shezad K. ; Bobo, William V. ; Clark, Matthew M. ; Rummans, Teresa A. / Effects of a multidisciplinary quality of life intervention on sleep quality in patients with advanced cancer receiving radiation therapy. In: Palliative and Supportive Care. 2019.
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