Effect of valve deformity on results and mitral regurgitation after inoue balloon commissurotomy

Ted Feldman, John D. Carroll, Jeffrey M. Isner, Robert J. Chisholm, David Holmes, Ali Massumi, Augusto D. Pichard, Howard C. Herrmann, Simon H. Stertzer, William W. O'Neill, Gerald Dorros, Ponnambalam Sundram, Thomas M. Bashore, K. Ramaswamy, Lisa S. Jones, Kanji Inoue

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

Background. The effect of valve deformity and patient age adversely affect the results of percutaneous transvenous mitral commissurotomy (PTMC) with conventional balloons. Methods and Results. These factors were characterized after PTMC with the Inoue balloon. The increases in mitral valve area and mitral regurgitation after the procedure were evaluated comparing echocardiographic score of 8 or less versus more than 8, age of less than 60 versus age of 60 years or more, and age of less than 70 versus age of 70 years or more. One hundred sixty-two patients (mean age, 52±14 years) were studied. For the entire group, mitral valve area increased from 1.0 to 1.8 cm2 (p<0.001). Valve area increased from 1.0±0.3 to 1.8±0.6 cm2 in patients with echocardiographic score of 8 or less (n = 102) and from 1.0±0.3 to 1.7±0.5 cm2 with echocardiographic score of more than 8 (n=44). Patients less than 60 years old (n = 104) had increases in valve area from 1.0±0.3 to 1.8±0.6 cm2 versus 1.0±0.4 to 1.8±0.6 cm2 for those 60 years old or older (n=50) (p=NS). There was no significant difference in resultant valve area when the age division was increased to less than 70 versus 70 years or more. Similarly, the percentage of patients with 2+ or greater increase in mitral regurgitation was not different for those with higher than for those with lower echocardiographic scores (4% versus 12%, p=NS), age of less than 60 versus age of 60 years or more (10% versus 10%, p=NS), or age of less than 70 versus age of 70 or more years (9% versus 18%, p=NS). Valve replacement for mitral régurgitation was performed in four patients (one emergency), all with echocardiographic scores of less than 8. Conclusions. Age and extent of valve deformity do not have significant effects on acute results of PTMC using the Inoue balloon. Unique balloon geometry or the controlled, stepwise balloon sizing may explain these acceptable acute results in patients with more-deformed valves.

Original languageEnglish (US)
Pages (from-to)180-187
Number of pages8
JournalCirculation
Volume85
Issue number1
DOIs
StatePublished - Jan 1 1992

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Mitral Valve Insufficiency
Mitral Valve
Emergencies

Keywords

  • Inoue balloon
  • Mitral stenosis
  • Percutaneous transvenous mitral commissurotomy
  • Valvuloplasty

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Feldman, T., Carroll, J. D., Isner, J. M., Chisholm, R. J., Holmes, D., Massumi, A., ... Inoue, K. (1992). Effect of valve deformity on results and mitral regurgitation after inoue balloon commissurotomy. Circulation, 85(1), 180-187. https://doi.org/10.1161/01.CIR.85.1.180

Effect of valve deformity on results and mitral regurgitation after inoue balloon commissurotomy. / Feldman, Ted; Carroll, John D.; Isner, Jeffrey M.; Chisholm, Robert J.; Holmes, David; Massumi, Ali; Pichard, Augusto D.; Herrmann, Howard C.; Stertzer, Simon H.; O'Neill, William W.; Dorros, Gerald; Sundram, Ponnambalam; Bashore, Thomas M.; Ramaswamy, K.; Jones, Lisa S.; Inoue, Kanji.

In: Circulation, Vol. 85, No. 1, 01.01.1992, p. 180-187.

Research output: Contribution to journalArticle

Feldman, T, Carroll, JD, Isner, JM, Chisholm, RJ, Holmes, D, Massumi, A, Pichard, AD, Herrmann, HC, Stertzer, SH, O'Neill, WW, Dorros, G, Sundram, P, Bashore, TM, Ramaswamy, K, Jones, LS & Inoue, K 1992, 'Effect of valve deformity on results and mitral regurgitation after inoue balloon commissurotomy', Circulation, vol. 85, no. 1, pp. 180-187. https://doi.org/10.1161/01.CIR.85.1.180
Feldman, Ted ; Carroll, John D. ; Isner, Jeffrey M. ; Chisholm, Robert J. ; Holmes, David ; Massumi, Ali ; Pichard, Augusto D. ; Herrmann, Howard C. ; Stertzer, Simon H. ; O'Neill, William W. ; Dorros, Gerald ; Sundram, Ponnambalam ; Bashore, Thomas M. ; Ramaswamy, K. ; Jones, Lisa S. ; Inoue, Kanji. / Effect of valve deformity on results and mitral regurgitation after inoue balloon commissurotomy. In: Circulation. 1992 ; Vol. 85, No. 1. pp. 180-187.
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abstract = "Background. The effect of valve deformity and patient age adversely affect the results of percutaneous transvenous mitral commissurotomy (PTMC) with conventional balloons. Methods and Results. These factors were characterized after PTMC with the Inoue balloon. The increases in mitral valve area and mitral regurgitation after the procedure were evaluated comparing echocardiographic score of 8 or less versus more than 8, age of less than 60 versus age of 60 years or more, and age of less than 70 versus age of 70 years or more. One hundred sixty-two patients (mean age, 52±14 years) were studied. For the entire group, mitral valve area increased from 1.0 to 1.8 cm2 (p<0.001). Valve area increased from 1.0±0.3 to 1.8±0.6 cm2 in patients with echocardiographic score of 8 or less (n = 102) and from 1.0±0.3 to 1.7±0.5 cm2 with echocardiographic score of more than 8 (n=44). Patients less than 60 years old (n = 104) had increases in valve area from 1.0±0.3 to 1.8±0.6 cm2 versus 1.0±0.4 to 1.8±0.6 cm2 for those 60 years old or older (n=50) (p=NS). There was no significant difference in resultant valve area when the age division was increased to less than 70 versus 70 years or more. Similarly, the percentage of patients with 2+ or greater increase in mitral regurgitation was not different for those with higher than for those with lower echocardiographic scores (4{\%} versus 12{\%}, p=NS), age of less than 60 versus age of 60 years or more (10{\%} versus 10{\%}, p=NS), or age of less than 70 versus age of 70 or more years (9{\%} versus 18{\%}, p=NS). Valve replacement for mitral r{\'e}gurgitation was performed in four patients (one emergency), all with echocardiographic scores of less than 8. Conclusions. Age and extent of valve deformity do not have significant effects on acute results of PTMC using the Inoue balloon. Unique balloon geometry or the controlled, stepwise balloon sizing may explain these acceptable acute results in patients with more-deformed valves.",
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T1 - Effect of valve deformity on results and mitral regurgitation after inoue balloon commissurotomy

AU - Feldman, Ted

AU - Carroll, John D.

AU - Isner, Jeffrey M.

AU - Chisholm, Robert J.

AU - Holmes, David

AU - Massumi, Ali

AU - Pichard, Augusto D.

AU - Herrmann, Howard C.

AU - Stertzer, Simon H.

AU - O'Neill, William W.

AU - Dorros, Gerald

AU - Sundram, Ponnambalam

AU - Bashore, Thomas M.

AU - Ramaswamy, K.

AU - Jones, Lisa S.

AU - Inoue, Kanji

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Background. The effect of valve deformity and patient age adversely affect the results of percutaneous transvenous mitral commissurotomy (PTMC) with conventional balloons. Methods and Results. These factors were characterized after PTMC with the Inoue balloon. The increases in mitral valve area and mitral regurgitation after the procedure were evaluated comparing echocardiographic score of 8 or less versus more than 8, age of less than 60 versus age of 60 years or more, and age of less than 70 versus age of 70 years or more. One hundred sixty-two patients (mean age, 52±14 years) were studied. For the entire group, mitral valve area increased from 1.0 to 1.8 cm2 (p<0.001). Valve area increased from 1.0±0.3 to 1.8±0.6 cm2 in patients with echocardiographic score of 8 or less (n = 102) and from 1.0±0.3 to 1.7±0.5 cm2 with echocardiographic score of more than 8 (n=44). Patients less than 60 years old (n = 104) had increases in valve area from 1.0±0.3 to 1.8±0.6 cm2 versus 1.0±0.4 to 1.8±0.6 cm2 for those 60 years old or older (n=50) (p=NS). There was no significant difference in resultant valve area when the age division was increased to less than 70 versus 70 years or more. Similarly, the percentage of patients with 2+ or greater increase in mitral regurgitation was not different for those with higher than for those with lower echocardiographic scores (4% versus 12%, p=NS), age of less than 60 versus age of 60 years or more (10% versus 10%, p=NS), or age of less than 70 versus age of 70 or more years (9% versus 18%, p=NS). Valve replacement for mitral régurgitation was performed in four patients (one emergency), all with echocardiographic scores of less than 8. Conclusions. Age and extent of valve deformity do not have significant effects on acute results of PTMC using the Inoue balloon. Unique balloon geometry or the controlled, stepwise balloon sizing may explain these acceptable acute results in patients with more-deformed valves.

AB - Background. The effect of valve deformity and patient age adversely affect the results of percutaneous transvenous mitral commissurotomy (PTMC) with conventional balloons. Methods and Results. These factors were characterized after PTMC with the Inoue balloon. The increases in mitral valve area and mitral regurgitation after the procedure were evaluated comparing echocardiographic score of 8 or less versus more than 8, age of less than 60 versus age of 60 years or more, and age of less than 70 versus age of 70 years or more. One hundred sixty-two patients (mean age, 52±14 years) were studied. For the entire group, mitral valve area increased from 1.0 to 1.8 cm2 (p<0.001). Valve area increased from 1.0±0.3 to 1.8±0.6 cm2 in patients with echocardiographic score of 8 or less (n = 102) and from 1.0±0.3 to 1.7±0.5 cm2 with echocardiographic score of more than 8 (n=44). Patients less than 60 years old (n = 104) had increases in valve area from 1.0±0.3 to 1.8±0.6 cm2 versus 1.0±0.4 to 1.8±0.6 cm2 for those 60 years old or older (n=50) (p=NS). There was no significant difference in resultant valve area when the age division was increased to less than 70 versus 70 years or more. Similarly, the percentage of patients with 2+ or greater increase in mitral regurgitation was not different for those with higher than for those with lower echocardiographic scores (4% versus 12%, p=NS), age of less than 60 versus age of 60 years or more (10% versus 10%, p=NS), or age of less than 70 versus age of 70 or more years (9% versus 18%, p=NS). Valve replacement for mitral régurgitation was performed in four patients (one emergency), all with echocardiographic scores of less than 8. Conclusions. Age and extent of valve deformity do not have significant effects on acute results of PTMC using the Inoue balloon. Unique balloon geometry or the controlled, stepwise balloon sizing may explain these acceptable acute results in patients with more-deformed valves.

KW - Inoue balloon

KW - Mitral stenosis

KW - Percutaneous transvenous mitral commissurotomy

KW - Valvuloplasty

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