TY - JOUR
T1 - Effect of spectral degradation and spatio-energy correlation in x-ray pcd for imaging
AU - Rajbhandary, Paurakh L.
AU - Hsieh, Scott S.
AU - Pelc, Norbert J.
N1 - Funding Information:
Manuscript received December 31, 2017; revised April 26, 2018 and April 30, 2018; accepted May 2, 2018. Date of publication May 8, 2018; date of current version July 31, 2018. This work was supported in part by Philips Healthcare and in part by NIH under Grant U01 EB017140. (Corresponding author: Paurakh L. Rajbhandary.) P. L. Rajbhandary is with the Department of Electrical Engineering, Stanford University, Stanford, CA 94305 USA (e-mail: paurakh@ stanford.edu).
Publisher Copyright:
© 2018 IEEE.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2018/8
Y1 - 2018/8
N2 - Charge sharing, scatter, and fluorescence events in a photon counting detector can result in counting of a single incident photon in multiple neighboring pixels, each at a fraction of the true energy. This causes energy distortion and correlation of data across energy bins in neighboring pixels (spatio-energy correlation), with the severity depending on the detector pixel size and detector material. If a 'macro-pixel' is formed by combining the counts from multiple adjacent small pixels, it will exhibit correlations across its energy bins. Understanding these effects can be crucial for detector design and for model-based imaging applications. This paper investigates the impact of these effects in basis material and effective monoenergetic estimates using the Cramér-Rao Lower Bound. To do so, we derive a correlation model for the multi-counting events. CdTe detectors with grids of pixels with side length of 250μm , 500μm , and 1 mm were compared, with binning of 4×4 , 2×2 , and 1×1 pixels, respectively, to keep the same net 1 mm 2 aperture constant. The same flux was applied to each. The mean and covariance matrix of measured photon counts were derived analytically using spatio-energy response functions precomputed from Monte Carlo simulations. Our results show that a 1 mm 2 macro-pixel with 250× 250 mu;m 2 sub-pixels shows 35% higher standard deviation than a single 1 mm 2 pixel for material-specific imaging, while the penalty for effective monoenergetic imaging is <10% compared with a single 1 mm 2 pixel. Potential benefits of sub-pixels (higher spatial resolution and lower pulse pile-up effects) are important but were not investigated here.
AB - Charge sharing, scatter, and fluorescence events in a photon counting detector can result in counting of a single incident photon in multiple neighboring pixels, each at a fraction of the true energy. This causes energy distortion and correlation of data across energy bins in neighboring pixels (spatio-energy correlation), with the severity depending on the detector pixel size and detector material. If a 'macro-pixel' is formed by combining the counts from multiple adjacent small pixels, it will exhibit correlations across its energy bins. Understanding these effects can be crucial for detector design and for model-based imaging applications. This paper investigates the impact of these effects in basis material and effective monoenergetic estimates using the Cramér-Rao Lower Bound. To do so, we derive a correlation model for the multi-counting events. CdTe detectors with grids of pixels with side length of 250μm , 500μm , and 1 mm were compared, with binning of 4×4 , 2×2 , and 1×1 pixels, respectively, to keep the same net 1 mm 2 aperture constant. The same flux was applied to each. The mean and covariance matrix of measured photon counts were derived analytically using spatio-energy response functions precomputed from Monte Carlo simulations. Our results show that a 1 mm 2 macro-pixel with 250× 250 mu;m 2 sub-pixels shows 35% higher standard deviation than a single 1 mm 2 pixel for material-specific imaging, while the penalty for effective monoenergetic imaging is <10% compared with a single 1 mm 2 pixel. Potential benefits of sub-pixels (higher spatial resolution and lower pulse pile-up effects) are important but were not investigated here.
KW - Charge Sharing
KW - K-Fluorescence Escape
KW - Material Decomposition
KW - Photon Counting X-Ray Detector
KW - Spatio-Energetic Correlation
KW - Spectral CT
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U2 - 10.1109/TMI.2018.2834369
DO - 10.1109/TMI.2018.2834369
M3 - Article
C2 - 29993882
AN - SCOPUS:85046752817
SN - 0278-0062
VL - 37
SP - 1910
EP - 1919
JO - IEEE Transactions on Medical Imaging
JF - IEEE Transactions on Medical Imaging
IS - 8
M1 - 8356096
ER -