Effect of Hepatitis C Positivity on Survival in Adult Patients Undergoing Heart Transplantation (from the United Network for Organ Sharing Database)

Sachin Kumar, Salil V. Deo, Salah E. Altarabsheh, Shannon M Dunlay, Nagaraju Sarabu, Basar Sareyyupoglu, Yakov Elgudin, Benjamin Medalion, Chantal ElAmm, Mahazarin Ginwalla, Michael Zacharias, Rodolpho Benatti, Guilherme H. Oliveira, Ahmet Kilic, Gregg C. Fonarow, Soon J. Park

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Concerns exist regarding orthotropic heart transplantation in hepatitis C virus (HCV) seropositive recipients. Thus, a national registry was accessed to evaluate early and late outcome in HCV seropositive recipients undergoing heart transplant. Retrospective analysis of the United Network for Organ Sharing registry (1991 to 2014) was performed to evaluate recipient profile and clinical outcome of patients with HCV seropositive (HCV +ve) and seronegative (HCV -ve). Adjusted results of early mortality and late survival were compared between cohorts. From 23,507 patients (mean age 52 years; 75% men), 481 (2%) were HCV +ve (mean age 52 years; 77% men). Annual proportion of HCV +ve recipients was comparable over the study period (range 1.3% to 2.7%; p = 0.2). The HCV +ve cohort had more African-American (22% vs 17%; p = 0.01), previous left ventricular assist device utilization (21% vs 14%; p

Original languageEnglish (US)
JournalAmerican Journal of Cardiology
DOIs
StateAccepted/In press - Feb 9 2016

    Fingerprint

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Kumar, S., Deo, S. V., Altarabsheh, S. E., Dunlay, S. M., Sarabu, N., Sareyyupoglu, B., Elgudin, Y., Medalion, B., ElAmm, C., Ginwalla, M., Zacharias, M., Benatti, R., Oliveira, G. H., Kilic, A., Fonarow, G. C., & Park, S. J. (Accepted/In press). Effect of Hepatitis C Positivity on Survival in Adult Patients Undergoing Heart Transplantation (from the United Network for Organ Sharing Database). American Journal of Cardiology. https://doi.org/10.1016/j.amjcard.2016.04.023