Abstract
Regional displacements of lung parenchyma due to respiratory movements at 1 G and 7 G(y) were studied in anesthetized dogs in the left decubitus position in a water-filled respirator that provided control of respiratory volumes and rate and minimized inertial shifts in position and shape of the thorax and abdominal contents and related effects on the lungs. Inspiratory movements at 1 G were relatively uniform, although regional volume increased more in the nondependent (right) lung than in the dependent (left) lung. Regional functional residual capacity (FRC) increased in the nondependent lung and decreased in the dependent lung during exposures to 7 G(y). The greatest inspiratory increase in volume occurred near the midlung, where regional FRC changed the least during acceleration. The decrease in dependent and increase in non-dependent lung volumes during acceleration are attributed to the increased weight and consequent downward displacement of the higher specific gravity mediastinal contents concomitantly with upward displacement of pulmonary gas, producing an exaggeration of the dependent-to-nondependent gradient in alveolar size.
Original language | English (US) |
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Pages (from-to) | 216-224 |
Number of pages | 9 |
Journal | Unknown Journal |
Volume | 44 |
Issue number | 2 |
DOIs | |
State | Published - 1978 |
ASJC Scopus subject areas
- Physiology
- Endocrinology