Effect of force environment on regional pulmonary displacements and volumes in dogs

James F Greenleaf, H. C. Smith, P. A. Chevalier, D. J. Sass, A. A. Bove, E. H. Wood

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Regional displacements of lung parenchyma due to respiratory movements at 1 G and 7 G(y) were studied in anesthetized dogs in the left decubitus position in a water-filled respirator that provided control of respiratory volumes and rate and minimized inertial shifts in position and shape of the thorax and abdominal contents and related effects on the lungs. Inspiratory movements at 1 G were relatively uniform, although regional volume increased more in the nondependent (right) lung than in the dependent (left) lung. Regional functional residual capacity (FRC) increased in the nondependent lung and decreased in the dependent lung during exposures to 7 G(y). The greatest inspiratory increase in volume occurred near the midlung, where regional FRC changed the least during acceleration. The decrease in dependent and increase in non-dependent lung volumes during acceleration are attributed to the increased weight and consequent downward displacement of the higher specific gravity mediastinal contents concomitantly with upward displacement of pulmonary gas, producing an exaggeration of the dependent-to-nondependent gradient in alveolar size.

Original languageEnglish (US)
Pages (from-to)216-224
Number of pages9
JournalJournal of Applied Physiology Respiratory Environmental and Exercise Physiology
Volume44
Issue number2
StatePublished - 1978

Fingerprint

Dogs
Lung
Functional Residual Capacity
Hypergravity
Specific Gravity
Mechanical Ventilators
Respiratory Rate
Thorax
Gases
Weights and Measures
Water

ASJC Scopus subject areas

  • Physiology
  • Endocrinology

Cite this

Effect of force environment on regional pulmonary displacements and volumes in dogs. / Greenleaf, James F; Smith, H. C.; Chevalier, P. A.; Sass, D. J.; Bove, A. A.; Wood, E. H.

In: Journal of Applied Physiology Respiratory Environmental and Exercise Physiology, Vol. 44, No. 2, 1978, p. 216-224.

Research output: Contribution to journalArticle

Greenleaf, James F ; Smith, H. C. ; Chevalier, P. A. ; Sass, D. J. ; Bove, A. A. ; Wood, E. H. / Effect of force environment on regional pulmonary displacements and volumes in dogs. In: Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 1978 ; Vol. 44, No. 2. pp. 216-224.
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