Effect of Demographics on Excretion of Key Urinary Factors Related to Kidney Stone Risk

Majuran Perinpam, Erin B. Ware, Jennifer A. Smith, Stephen T Turner, Sharon L R Kardia, John C Lieske

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective To investigate the effect of demographics including age and sex on excretion of 4 key urinary factors (calcium [Ca], magnesium [Mg], oxalate and uric acid [UA]) related to kidney stone risk. Methods Twenty-four-hour urine samples were collected from non-Hispanic white sibships in Rochester, MN. Height, weight, blood pressure, serum creatinine, and cystatin C were measured. Diet was assessed using the Viocare food frequency questionnaire. Effects of demographics and dietary elements on urinary excretions were evaluated in univariate, multivariate, and interaction models that included age, sex, and body mass index (BMI). Results Samples were available from 709 individuals. In multivariate models, sex was a significant predictor of all 4 urinary factors, age was significant for all but UA excretion, and serum creatinine was significant only for Ca and Mg excretion (P

Original languageEnglish (US)
Pages (from-to)690-696
Number of pages7
JournalUrology
Volume86
Issue number4
DOIs
StatePublished - Oct 1 2015

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Kidney Calculi
Demography
Uric Acid
Creatinine
Cystatin C
Oxalic Acid
Calcium Oxalate
Age Factors
Serum
Magnesium
Body Mass Index
Urine
Diet
Blood Pressure
Calcium
Weights and Measures
Food

ASJC Scopus subject areas

  • Urology

Cite this

Effect of Demographics on Excretion of Key Urinary Factors Related to Kidney Stone Risk. / Perinpam, Majuran; Ware, Erin B.; Smith, Jennifer A.; Turner, Stephen T; Kardia, Sharon L R; Lieske, John C.

In: Urology, Vol. 86, No. 4, 01.10.2015, p. 690-696.

Research output: Contribution to journalArticle

Perinpam, Majuran ; Ware, Erin B. ; Smith, Jennifer A. ; Turner, Stephen T ; Kardia, Sharon L R ; Lieske, John C. / Effect of Demographics on Excretion of Key Urinary Factors Related to Kidney Stone Risk. In: Urology. 2015 ; Vol. 86, No. 4. pp. 690-696.
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