TY - JOUR
T1 - Effect of Cognitive Status on the Receipt of Procedures Requiring Anesthesia and Critical Care Admissions in Older Adults
AU - Schulte, Phillip J.
AU - Martin, David P.
AU - Deljou, Atousa
AU - Sabov, Moldovan
AU - Roberts, Rosebud O.
AU - Knopman, David S.
AU - Petersen, Ronald C.
AU - Weingarten, Toby N.
AU - Hanson, Andrew C.
AU - Schroeder, Darrell R.
AU - Warner, David O.
AU - Sprung, Juraj
N1 - Funding Information:
Grant Support: This study was made possible by the Rochester Epidemiology Project (grant number R01-AG034676; Principal Investigators: Walter A. Rocca, MD, MPH, and Jennifer L. St Sauver, PhD). It was also supported by grants P50 AG016574 and RP (R.C.P.) from the National Institutes of Health (NIH), by the Robert H. and Clarice Smith and Abigail van Buren Alzheimer's Disease Research Program, by the Mayo Clinic Center for Translational Sciences Activities, and by grant UL1 TR000135 from the National Center for Advancing Translational Sciences. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Financial support for statistical analyses was provided by the Department of Anesthesiology, Mayo Clinic.
Publisher Copyright:
© 2018 Mayo Foundation for Medical Education and Research
PY - 2018/11
Y1 - 2018/11
N2 - Objective: To investigate whether older adults with mild cognitive impairment (MCI) or dementia have higher rates of procedures requiring general anesthesia or intensive care unit (ICU) admissions compared with cognitively normal (CN) patients. Patients and Methods: A population-based cohort, 70 to 89 years old at enrollment, underwent clinical and longitudinal neurocognitive testing to identify those with MCI and dementia. We analyzed the effects of cognitive status (CN, MCI, or dementia) at entry into the study from October 1, 2004, through December 31, 2014, on the risk of receiving procedures requiring surgical anesthesia and ICU admission. Results: Of 2436 participants, 1977 (81%) were CN, 387 (16%) had MCI, and 72 (3%) had dementia. Cognitively impaired individuals were sicker. Compared with CN individuals, the likelihood of receiving a procedure requiring anesthesia was similar in participants with MCI (adjusted hazard ratio [aHR]=0.98; P=.78). Participants with dementia were less likely to receive these procedures (aHR=0.50; P=.02). Compared with CN participants, the likelihood of ICU admission for any indication was increased for those with MCI (aHR=1.24; P=.03) and dementia (aHR=1.59; P=.04). Admissions to the ICU after procedures were not different in patients with either MCI or dementia (aHR=0.96; P=.83 and aHR=1.01; P=.98, respectively). Conclusion: Patients with MCI or dementia are not more likely to undergo surgery, and neither are they more likely to require ICU admission after procedures. An increased rate of nonsurgical ICU admissions requires vigilance to prevent deterioration of nonsurgical diseases that may lead to ICU admissions.
AB - Objective: To investigate whether older adults with mild cognitive impairment (MCI) or dementia have higher rates of procedures requiring general anesthesia or intensive care unit (ICU) admissions compared with cognitively normal (CN) patients. Patients and Methods: A population-based cohort, 70 to 89 years old at enrollment, underwent clinical and longitudinal neurocognitive testing to identify those with MCI and dementia. We analyzed the effects of cognitive status (CN, MCI, or dementia) at entry into the study from October 1, 2004, through December 31, 2014, on the risk of receiving procedures requiring surgical anesthesia and ICU admission. Results: Of 2436 participants, 1977 (81%) were CN, 387 (16%) had MCI, and 72 (3%) had dementia. Cognitively impaired individuals were sicker. Compared with CN individuals, the likelihood of receiving a procedure requiring anesthesia was similar in participants with MCI (adjusted hazard ratio [aHR]=0.98; P=.78). Participants with dementia were less likely to receive these procedures (aHR=0.50; P=.02). Compared with CN participants, the likelihood of ICU admission for any indication was increased for those with MCI (aHR=1.24; P=.03) and dementia (aHR=1.59; P=.04). Admissions to the ICU after procedures were not different in patients with either MCI or dementia (aHR=0.96; P=.83 and aHR=1.01; P=.98, respectively). Conclusion: Patients with MCI or dementia are not more likely to undergo surgery, and neither are they more likely to require ICU admission after procedures. An increased rate of nonsurgical ICU admissions requires vigilance to prevent deterioration of nonsurgical diseases that may lead to ICU admissions.
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U2 - 10.1016/j.mayocp.2018.06.021
DO - 10.1016/j.mayocp.2018.06.021
M3 - Article
C2 - 30274907
AN - SCOPUS:85054035416
SN - 0025-6196
VL - 93
SP - 1552
EP - 1562
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
IS - 11
ER -