Effect of body orientation on regional lung expansion in dog and sloth

E. A. Hoffman, E. L. Ritman

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Recent studies using fast multisliced X-ray computed tomography have demonstrated a ventral-dorsal gradient of fractional lung air content (3.29% air/cm lung height) in supine dogs and an essentially uniform ventral-dorsal air content distribution in the prone dogs [mean = 66 ± 0.6% (SE) air content]. Since the prone orientation is the dog's normal body posture, we sought to study an animal whose normal body posture was 'opposite' to that of the dog. Four two-toed sloths were scanned in the Dynamic Spatial Reconstructor in the prone and supine postures. A supine fractional air content gradient was demonstrated with a regression equation of y = 2.09x + 74.3 (r = 0.92), were y is percent air content and x is vertical height in the lung, and ventral-dorsal air content distribution in the prone posture was uniform with a mean of 85 ± 0.4% (SE) air content. The low functional residual capacity lung density in the sloth was attributable to unusually large alveoli. The mean heart volume-to-body weight ratio in the dogs was 16.4 ± 0.6 (SE) ml/kg and that in the sloth was 7.3 ± 0.4 (SE) ml/kg. Mean lung volume-to-body weight ratios for dogs and sloths were 57 ± 7 (SE) and 89 ± 6 ml/kg, respectively. Of particular interest was the fact that large changes in prone vs. supine rib cage and diaphragm geometry previously found in dogs did not occur in sloths, though significant alterations of ventral and dorsal lung geometry prone vs. supine were demonstrated, and lung shape changes in both dog and sloth are attributable to shifts in the intrathoracic position of mediastinal structures.

Original languageEnglish (US)
Pages (from-to)481-491
Number of pages11
JournalJournal of Applied Physiology
Volume59
Issue number2
StatePublished - 1985

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Sloths
Air
Dogs
Lung
Posture
Body Weight
Functional Residual Capacity
Cardiac Volume
X Ray Computed Tomography
Diaphragm

ASJC Scopus subject areas

  • Endocrinology
  • Physiology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Effect of body orientation on regional lung expansion in dog and sloth. / Hoffman, E. A.; Ritman, E. L.

In: Journal of Applied Physiology, Vol. 59, No. 2, 1985, p. 481-491.

Research output: Contribution to journalArticle

Hoffman, E. A. ; Ritman, E. L. / Effect of body orientation on regional lung expansion in dog and sloth. In: Journal of Applied Physiology. 1985 ; Vol. 59, No. 2. pp. 481-491.
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