Abstract
Aim: Obesity is a major cardiovascular (CV) risk factor. Bariatric surgery (BSx) is an approved therapeutic alternative for classII-III obesity, but little evidence focuses on older adults. We assessed the effect of BSx on cardiometabolic variables and long-term CV risk in older adults. Methods: We carried out a population-based, observational study from 1990-2009, of 40 consecutive elderly (age ≥60 years) residents of Olmsted County, MN, USA, with classII-III obesity treated with BSx at a University-based, academic health center. Data were obtained from the Rochester Epidemiology Project. Metabolic syndrome (MetS) was defined using American Heart Association/National Heart, Lung, Blood Institute (AHA/NHLBI) criteria (increased triglycerides, low high-density lipoprotein, increased blood pressure, increased glucose and body mass index as a modified measure of obesity instead of waist circumference). Change in CV risk factors, MetS prevalence, and impact on predicted CV risk using the Framingham risk score was ascertained at 1 year postoperatively and assessed statistically. Results: Mean age and body mass index were 64.4±3.7 and 45.0±6.3kg/m<sup>2</sup>, respectively, and 28 out of 40 (70%) were women. One participant died during the 11-month study period after BSx from respiratory complications related to BSx, and one participant died at 2 years. Percentage of excess weight loss decreased by 57.5% at 1 year. Prevalence 1 year after BSx decreased for diabetes (57.5% to 22.5%; P<0.03), hypertension 87.5% to 73.7% (P=0.003), dyslipidemia (80% to 42.5%; P<0.001) and sleep apnea (62.5% to 23.7%; P<0.001).MetS prevalence decreased from 80% to 45% (P<0.002). Baseline risk was 14.1%, which changed at follow up at 8.2%. Conclusions: In older adults, BSx induces considerable weight loss, improves CV risk factors, decreases MetS prevalence and is an effective treatment in this population.
| Original language | English (US) |
|---|---|
| Journal | Geriatrics and Gerontology International |
| DOIs | |
| State | Accepted/In press - 2015 |
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Keywords
- Bariatric surgery
- Elderly
- Framingham risk
- Metabolic risk
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Gerontology
- Health(social science)
Cite this
Effect of bariatric surgery on cardiometabolic risk in elderly patients : A population-based study. / Batsis, John A.; Miranda, William R.; Prasad, Chaithra; Collazo-Clavell, Maria L.; Sarr, Michael G.; Somers, Virend; Lopez-Jimenez, Francisco.
In: Geriatrics and Gerontology International, 2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of bariatric surgery on cardiometabolic risk in elderly patients
T2 - A population-based study
AU - Batsis, John A.
AU - Miranda, William R.
AU - Prasad, Chaithra
AU - Collazo-Clavell, Maria L.
AU - Sarr, Michael G.
AU - Somers, Virend
AU - Lopez-Jimenez, Francisco
PY - 2015
Y1 - 2015
N2 - Aim: Obesity is a major cardiovascular (CV) risk factor. Bariatric surgery (BSx) is an approved therapeutic alternative for classII-III obesity, but little evidence focuses on older adults. We assessed the effect of BSx on cardiometabolic variables and long-term CV risk in older adults. Methods: We carried out a population-based, observational study from 1990-2009, of 40 consecutive elderly (age ≥60 years) residents of Olmsted County, MN, USA, with classII-III obesity treated with BSx at a University-based, academic health center. Data were obtained from the Rochester Epidemiology Project. Metabolic syndrome (MetS) was defined using American Heart Association/National Heart, Lung, Blood Institute (AHA/NHLBI) criteria (increased triglycerides, low high-density lipoprotein, increased blood pressure, increased glucose and body mass index as a modified measure of obesity instead of waist circumference). Change in CV risk factors, MetS prevalence, and impact on predicted CV risk using the Framingham risk score was ascertained at 1 year postoperatively and assessed statistically. Results: Mean age and body mass index were 64.4±3.7 and 45.0±6.3kg/m2, respectively, and 28 out of 40 (70%) were women. One participant died during the 11-month study period after BSx from respiratory complications related to BSx, and one participant died at 2 years. Percentage of excess weight loss decreased by 57.5% at 1 year. Prevalence 1 year after BSx decreased for diabetes (57.5% to 22.5%; P<0.03), hypertension 87.5% to 73.7% (P=0.003), dyslipidemia (80% to 42.5%; P<0.001) and sleep apnea (62.5% to 23.7%; P<0.001).MetS prevalence decreased from 80% to 45% (P<0.002). Baseline risk was 14.1%, which changed at follow up at 8.2%. Conclusions: In older adults, BSx induces considerable weight loss, improves CV risk factors, decreases MetS prevalence and is an effective treatment in this population.
AB - Aim: Obesity is a major cardiovascular (CV) risk factor. Bariatric surgery (BSx) is an approved therapeutic alternative for classII-III obesity, but little evidence focuses on older adults. We assessed the effect of BSx on cardiometabolic variables and long-term CV risk in older adults. Methods: We carried out a population-based, observational study from 1990-2009, of 40 consecutive elderly (age ≥60 years) residents of Olmsted County, MN, USA, with classII-III obesity treated with BSx at a University-based, academic health center. Data were obtained from the Rochester Epidemiology Project. Metabolic syndrome (MetS) was defined using American Heart Association/National Heart, Lung, Blood Institute (AHA/NHLBI) criteria (increased triglycerides, low high-density lipoprotein, increased blood pressure, increased glucose and body mass index as a modified measure of obesity instead of waist circumference). Change in CV risk factors, MetS prevalence, and impact on predicted CV risk using the Framingham risk score was ascertained at 1 year postoperatively and assessed statistically. Results: Mean age and body mass index were 64.4±3.7 and 45.0±6.3kg/m2, respectively, and 28 out of 40 (70%) were women. One participant died during the 11-month study period after BSx from respiratory complications related to BSx, and one participant died at 2 years. Percentage of excess weight loss decreased by 57.5% at 1 year. Prevalence 1 year after BSx decreased for diabetes (57.5% to 22.5%; P<0.03), hypertension 87.5% to 73.7% (P=0.003), dyslipidemia (80% to 42.5%; P<0.001) and sleep apnea (62.5% to 23.7%; P<0.001).MetS prevalence decreased from 80% to 45% (P<0.002). Baseline risk was 14.1%, which changed at follow up at 8.2%. Conclusions: In older adults, BSx induces considerable weight loss, improves CV risk factors, decreases MetS prevalence and is an effective treatment in this population.
KW - Bariatric surgery
KW - Elderly
KW - Framingham risk
KW - Metabolic risk
UR - http://www.scopus.com/inward/record.url?scp=84930339355&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84930339355&partnerID=8YFLogxK
U2 - 10.1111/ggi.12527
DO - 10.1111/ggi.12527
M3 - Article
C2 - 26017642
AN - SCOPUS:84930339355
JO - Geriatrics and Gerontology International
JF - Geriatrics and Gerontology International
SN - 1447-0594
ER -