Effect of army basic training in sickle-cell trait

I. M. Weisman, J. Zeballos, T. W. Martin, Bruce David Johnson

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

In order to determine if sickle-cell trait (SCT) represents an inherent adverse effect on response to training, we objectively evaluated exercise performance in 22 healthy, black men with SCT (hemoglobin AS) and 15 controls (hemoglobin AA) before and after seven weeks of army basic training at an altitude of 1270 m. An incremental exercise test to exhaustion on a cycle ergometer was used. Before basic training, peak exercise measurements did not reveal significant differences between groups other than a slightly lower, albeit significant, value for oxygen uptake (V̇O2) per kilogram (42 ± 1 vs 45 ± 1.4 mL/min per kilogram) for the SCT group. Both groups experienced modest overall cardiovascular improvement reflected in both peak and submaximal exercise response. No statistically significant difference was observed between the SCT and the control groups at the end of basic training for any of the measured variables at peak exercise, including power (258 ± 6 vs 266 ± 9W), V̇O2 (3.24 ± .06 vs 3.36 ± .16 L/min), V̇O2 per kilogram (46 ± 0.7 vs 46 ± 1.2), minute ventilation (138 ± 4 vs 147 ± 8 L/min), heart rate (185 ± 2 vs 184 ± 3 beats per minute), oxygen pulse (17.6 ± .3 vs 18.4 ± 1 mL/min per beat), as well as anaerobic threshold (1.81 ± .04 vs 1.80 ± .06 L/min), respectively. No medical problems directly attributed to SCT were reported; it remains uncertain, however, whether a seizure experienced by one of the other SCT basic trainees after a two-mile run was SCT related. The results of this study would, therefore, suggest that for the majority of individuals who possess SCT, the response to the moderate training regimen provided by army basic training is not impaired.

Original languageEnglish (US)
Pages (from-to)1140-1144
Number of pages5
JournalArchives of Internal Medicine
Volume148
Issue number5
StatePublished - 1988
Externally publishedYes

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Sickle Cell Trait
Exercise
Oxygen
Anaerobic Threshold
Exercise Test
Ventilation
Seizures
Heart Rate
Control Groups

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Weisman, I. M., Zeballos, J., Martin, T. W., & Johnson, B. D. (1988). Effect of army basic training in sickle-cell trait. Archives of Internal Medicine, 148(5), 1140-1144.

Effect of army basic training in sickle-cell trait. / Weisman, I. M.; Zeballos, J.; Martin, T. W.; Johnson, Bruce David.

In: Archives of Internal Medicine, Vol. 148, No. 5, 1988, p. 1140-1144.

Research output: Contribution to journalArticle

Weisman, IM, Zeballos, J, Martin, TW & Johnson, BD 1988, 'Effect of army basic training in sickle-cell trait', Archives of Internal Medicine, vol. 148, no. 5, pp. 1140-1144.
Weisman IM, Zeballos J, Martin TW, Johnson BD. Effect of army basic training in sickle-cell trait. Archives of Internal Medicine. 1988;148(5):1140-1144.
Weisman, I. M. ; Zeballos, J. ; Martin, T. W. ; Johnson, Bruce David. / Effect of army basic training in sickle-cell trait. In: Archives of Internal Medicine. 1988 ; Vol. 148, No. 5. pp. 1140-1144.
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