Effect of age on human gastric and small bowel motility

Alexander Fich, Michael Camilleri, Sidney F. Phillips

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

To test the hypothesis that age alters fasting and postprandial antral and intestinal motility in humans, we studied 23 patients, aged 18–39 years (median 28), and 13 patients, aged 40–69 years (median 49). All were having gastrointestinal symptoms, but in none was there objective clinical, radiologic, or endoscopic features of bowel disease, and manometry of the stomach and proximal small bowel was normal. We quantitated certain parameters of fasting intestinal motility and postprandial antral and jejunal motility. There were no significant differences in the interval between interdigestive motor complexes (IMC), duration, propagation velocity, or maximum number of contractions during phase III of the IMC, or postprandial antral and jejunal motility indices. The postprandial indices show a very similar distribution in each decade. Thus, in selected patients with unexplained gastrointestinal symptoms but no objective features of gut disease, quantifiable gastric and small bowel motility parameters do not differ in the age groups 18–39 and 40–69 years.

Original languageEnglish (US)
Pages (from-to)416-420
Number of pages5
JournalJournal of clinical gastroenterology
Volume11
Issue number4
DOIs
StatePublished - Aug 1989

Keywords

  • Aging
  • Antral motility
  • Interdigestive motor complex
  • Small bowel motility
  • Upper gastrointestinal manometry

ASJC Scopus subject areas

  • Gastroenterology

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