Editorial: Fecal granins in IBS: Cause or indicator of intestinal or colonic irritation

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Ohman et al. report increased fecal granins in patients with irritable bowel syndrome (IBS). Several interesting questions arise from their observations. Are the granins a cause of the pathophysiology or phenotype in IBS? Is the elevation of granins specific to IBS? What is the cause of increased fecal granin levels? Can fecal granin levels be used to diagnose IBS? Are increased fecal granins an expression of intestinal or colonic irritation? This paper adds to the body of evidence suggesting there are gastrointestinal disturbances in IBS; understanding these disturbances may provide clues to its pathogenesis and optimize management.

Original languageEnglish (US)
Pages (from-to)448-450
Number of pages3
JournalAmerican Journal of Gastroenterology
Volume107
Issue number3
DOIs
StatePublished - Mar 2012

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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