Editorial

Autoimmune Pancreatitis in Children: Is This a New Subtype of Disease or Early-Onset Idiopathic Duct-Centric Chronic Pancreatitis?

Phil A. Hart, Suresh T Chari

Research output: Contribution to journalReview article

Abstract

The term autoimmune pancreatitis (AIP) encompasses two distinct steroid-responsive pancreatitides, type 1 AIP and idiopathic duct-centric pancreatitis (IDCP) (or type 2 AIP). The current study describes cases of both AIP subtypes in a pediatric population. A comparison of the clinical profile of the described cohort with published data strongly suggests the majority of patients in the current cohort had IDCP. Since relapse rates in IDCP are low and long-term maintenance therapy is not required for IDCP, this has implications for prognosis and therapy. However, longer follow-up is needed to more accurately determine if onset during childhood leads to a different disease course.

Original languageEnglish (US)
Pages (from-to)1613-1614
Number of pages2
JournalAmerican Journal of Gastroenterology
Volume112
Issue number10
DOIs
StatePublished - Oct 1 2017

Fingerprint

Chronic Pancreatitis
Pancreatitis
Steroids
Pediatrics
Recurrence
Therapeutics

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

@article{2d8b800fac934458afbee72a52bbdb64,
title = "Editorial: Autoimmune Pancreatitis in Children: Is This a New Subtype of Disease or Early-Onset Idiopathic Duct-Centric Chronic Pancreatitis?",
abstract = "The term autoimmune pancreatitis (AIP) encompasses two distinct steroid-responsive pancreatitides, type 1 AIP and idiopathic duct-centric pancreatitis (IDCP) (or type 2 AIP). The current study describes cases of both AIP subtypes in a pediatric population. A comparison of the clinical profile of the described cohort with published data strongly suggests the majority of patients in the current cohort had IDCP. Since relapse rates in IDCP are low and long-term maintenance therapy is not required for IDCP, this has implications for prognosis and therapy. However, longer follow-up is needed to more accurately determine if onset during childhood leads to a different disease course.",
author = "Hart, {Phil A.} and Chari, {Suresh T}",
year = "2017",
month = "10",
day = "1",
doi = "10.1038/ajg.2017.236",
language = "English (US)",
volume = "112",
pages = "1613--1614",
journal = "American Journal of Gastroenterology",
issn = "0002-9270",
publisher = "Nature Publishing Group",
number = "10",

}

TY - JOUR

T1 - Editorial

T2 - Autoimmune Pancreatitis in Children: Is This a New Subtype of Disease or Early-Onset Idiopathic Duct-Centric Chronic Pancreatitis?

AU - Hart, Phil A.

AU - Chari, Suresh T

PY - 2017/10/1

Y1 - 2017/10/1

N2 - The term autoimmune pancreatitis (AIP) encompasses two distinct steroid-responsive pancreatitides, type 1 AIP and idiopathic duct-centric pancreatitis (IDCP) (or type 2 AIP). The current study describes cases of both AIP subtypes in a pediatric population. A comparison of the clinical profile of the described cohort with published data strongly suggests the majority of patients in the current cohort had IDCP. Since relapse rates in IDCP are low and long-term maintenance therapy is not required for IDCP, this has implications for prognosis and therapy. However, longer follow-up is needed to more accurately determine if onset during childhood leads to a different disease course.

AB - The term autoimmune pancreatitis (AIP) encompasses two distinct steroid-responsive pancreatitides, type 1 AIP and idiopathic duct-centric pancreatitis (IDCP) (or type 2 AIP). The current study describes cases of both AIP subtypes in a pediatric population. A comparison of the clinical profile of the described cohort with published data strongly suggests the majority of patients in the current cohort had IDCP. Since relapse rates in IDCP are low and long-term maintenance therapy is not required for IDCP, this has implications for prognosis and therapy. However, longer follow-up is needed to more accurately determine if onset during childhood leads to a different disease course.

UR - http://www.scopus.com/inward/record.url?scp=85030630550&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85030630550&partnerID=8YFLogxK

U2 - 10.1038/ajg.2017.236

DO - 10.1038/ajg.2017.236

M3 - Review article

VL - 112

SP - 1613

EP - 1614

JO - American Journal of Gastroenterology

JF - American Journal of Gastroenterology

SN - 0002-9270

IS - 10

ER -