Ectopic production of human chorionic gonadotropin: A case report

Charles Erlichman; J. F. Pringle; I. C. Quirt

doi:10.1002/mpo.2950060204

Ectopic production of human chorionic gonadotropin: A case report

Charles Erlichman, J. F. Pringle, I. C. Quirt

Medical Oncology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The ectopic production of the β‐subunit of human chorionic gonadotropin (hCG) is described in a patient with an anaplastic carcinoma. After chemotherapy the marker decreased in a logarithmic fashion to undetectable levels but the neoplasm progressed and the patient died. The specificity of the β‐subunit of hCG is discussed. Discordance of the marker and clinical disease is pointed out, and several possible explanations are outlined. The lack of specificity of the β‐subunit of hCG and the discordance that it may exhibit means that its use in diagnosing and following disease progression may be limited.

Original language	English (US)
Pages (from-to)	115-119
Number of pages	5
Journal	Medical and Pediatric Oncology
Volume	6
Issue number	2
DOIs	https://doi.org/10.1002/mpo.2950060204
State	Published - 1979

Keywords

anaplastic carcinoma
ectopic hormone production
tumour marker
β‐subunit of hCG

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Oncology
Cancer Research

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10.1002/mpo.2950060204

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title = "Ectopic production of human chorionic gonadotropin: A case report",

abstract = "The ectopic production of the β‐subunit of human chorionic gonadotropin (hCG) is described in a patient with an anaplastic carcinoma. After chemotherapy the marker decreased in a logarithmic fashion to undetectable levels but the neoplasm progressed and the patient died. The specificity of the β‐subunit of hCG is discussed. Discordance of the marker and clinical disease is pointed out, and several possible explanations are outlined. The lack of specificity of the β‐subunit of hCG and the discordance that it may exhibit means that its use in diagnosing and following disease progression may be limited.",

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author = "Charles Erlichman and Pringle, {J. F.} and Quirt, {I. C.}",

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AU - Quirt, I. C.

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AB - The ectopic production of the β‐subunit of human chorionic gonadotropin (hCG) is described in a patient with an anaplastic carcinoma. After chemotherapy the marker decreased in a logarithmic fashion to undetectable levels but the neoplasm progressed and the patient died. The specificity of the β‐subunit of hCG is discussed. Discordance of the marker and clinical disease is pointed out, and several possible explanations are outlined. The lack of specificity of the β‐subunit of hCG and the discordance that it may exhibit means that its use in diagnosing and following disease progression may be limited.

KW - anaplastic carcinoma

KW - ectopic hormone production

KW - tumour marker

KW - β‐subunit of hCG

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Ectopic production of human chorionic gonadotropin: A case report

Abstract

Keywords

ASJC Scopus subject areas

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