Ectopic production of human chorionic gonadotropin: A case report

Charles Erlichman, J. F. Pringle, I. C. Quirt

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The ectopic production of the β‐subunit of human chorionic gonadotropin (hCG) is described in a patient with an anaplastic carcinoma. After chemotherapy the marker decreased in a logarithmic fashion to undetectable levels but the neoplasm progressed and the patient died. The specificity of the β‐subunit of hCG is discussed. Discordance of the marker and clinical disease is pointed out, and several possible explanations are outlined. The lack of specificity of the β‐subunit of hCG and the discordance that it may exhibit means that its use in diagnosing and following disease progression may be limited.

Original languageEnglish (US)
Pages (from-to)115-119
Number of pages5
JournalMedical and Pediatric Oncology
Volume6
Issue number2
DOIs
StatePublished - 1979

    Fingerprint

Keywords

  • anaplastic carcinoma
  • ectopic hormone production
  • tumour marker
  • β‐subunit of hCG

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Cancer Research

Cite this