Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015

Emmie De Wit; Kyle Rosenke; Robert J. Fischer; Andrea Marzi; Joseph Prescott; Trenton Bushmaker; Neeltje Van Doremalen; Shannon L. Emery; Darryl Falzarano; Friederike Feldmann; Allison Groseth; Thomas Hoenen; Bonventure Juma; Kristin L. McNally; Melvin Ochieng; Victor Omballa; Clayton O. Onyango; Collins Owuor; Thomas Rowe; David Safronetz; Joshua Self; Brandi N. Williamson; Galina Zemtsova; Allen Grolla; Gary Kobinger; Mark Rayfield; Ute Ströher; James E. Strong; Sonja M. Best; Hideki Ebihara; Kathryn C. Zoon; Stuart T. Nichol; Tolbert G. Nyenswah; Fatorma K. Bolay; Moses Massaquoi; Heinz Feldmann; Barry Fields

doi:10.1093/infdis/jiw216

Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015

Emmie De Wit, Kyle Rosenke, Robert J. Fischer, Andrea Marzi, Joseph Prescott, Trenton Bushmaker, Neeltje Van Doremalen, Shannon L. Emery, Darryl Falzarano, Friederike Feldmann, Allison Groseth, Thomas Hoenen, Bonventure Juma, Kristin L. McNally, Melvin Ochieng, Victor Omballa, Clayton O. Onyango, Collins Owuor, Thomas Rowe, David SafronetzJoshua Self, Brandi N. Williamson, Galina Zemtsova, Allen Grolla, Gary Kobinger, Mark Rayfield, Ute Ströher, James E. Strong, Sonja M. Best, Hideki Ebihara, Kathryn C. Zoon, Stuart T. Nichol, Tolbert G. Nyenswah, Fatorma K. Bolay, Moses Massaquoi, Heinz Feldmann, Barry Fields

Molecular Medicine

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

West Africa experienced the first epidemic of Ebola virus infection, with by far the greatest number of cases in Guinea, Sierra Leone, and Liberia. The unprecedented epidemic triggered an unparalleled response, including the deployment of multiple Ebola treatment units and mobile/field diagnostic laboratories. The National Institute of Allergy and Infectious Diseases and the Centers for Disease Control and Prevention deployed a joint laboratory to Monrovia, Liberia, in August 2014 to support the newly founded Ebola treatment unit at the Eternal Love Winning Africa (ELWA) campus. The laboratory operated initially out of a tent structure but quickly moved into a fixed-wall building owing to severe weather conditions, the need for increased security, and the high sample volume. Until May 2015, when the laboratory closed, the site handled close to 6000 clinical specimens for Ebola virus diagnosis and supported the medical staff in case patient management. Laboratory operation and safety, as well as Ebola virus diagnostic assays, are described and discussed; in addition, lessons learned for future deployments are reviewed.

Original language	English (US)
Pages (from-to)	S169-S176
Journal	Journal of Infectious Diseases
Volume	214
DOIs	https://doi.org/10.1093/infdis/jiw216
State	Published - Oct 15 2016

Keywords

Diagnostics
Ebola virus
Epidemic
Mobile laboratory
West Africa

ASJC Scopus subject areas

Immunology and Allergy
Infectious Diseases

Access to Document

10.1093/infdis/jiw216

Cite this

De Wit, E., Rosenke, K., Fischer, R. J., Marzi, A., Prescott, J., Bushmaker, T., Van Doremalen, N., Emery, S. L., Falzarano, D., Feldmann, F., Groseth, A., Hoenen, T., Juma, B., McNally, K. L., Ochieng, M., Omballa, V., Onyango, C. O., Owuor, C., Rowe, T., ... Fields, B. (2016). Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015. Journal of Infectious Diseases, 214, S169-S176. https://doi.org/10.1093/infdis/jiw216

De Wit, E, Rosenke, K, Fischer, RJ, Marzi, A, Prescott, J, Bushmaker, T, Van Doremalen, N, Emery, SL, Falzarano, D, Feldmann, F, Groseth, A, Hoenen, T, Juma, B, McNally, KL, Ochieng, M, Omballa, V, Onyango, CO, Owuor, C, Rowe, T, Safronetz, D, Self, J, Williamson, BN, Zemtsova, G, Grolla, A, Kobinger, G, Rayfield, M, Ströher, U, Strong, JE, Best, SM, Ebihara, H, Zoon, KC, Nichol, ST, Nyenswah, TG, Bolay, FK, Massaquoi, M, Feldmann, H & Fields, B 2016, 'Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015', Journal of Infectious Diseases, vol. 214, pp. S169-S176. https://doi.org/10.1093/infdis/jiw216

@article{096e2729535b4aa4834bf5ee412dacd1,

title = "Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015",

abstract = "West Africa experienced the first epidemic of Ebola virus infection, with by far the greatest number of cases in Guinea, Sierra Leone, and Liberia. The unprecedented epidemic triggered an unparalleled response, including the deployment of multiple Ebola treatment units and mobile/field diagnostic laboratories. The National Institute of Allergy and Infectious Diseases and the Centers for Disease Control and Prevention deployed a joint laboratory to Monrovia, Liberia, in August 2014 to support the newly founded Ebola treatment unit at the Eternal Love Winning Africa (ELWA) campus. The laboratory operated initially out of a tent structure but quickly moved into a fixed-wall building owing to severe weather conditions, the need for increased security, and the high sample volume. Until May 2015, when the laboratory closed, the site handled close to 6000 clinical specimens for Ebola virus diagnosis and supported the medical staff in case patient management. Laboratory operation and safety, as well as Ebola virus diagnostic assays, are described and discussed; in addition, lessons learned for future deployments are reviewed.",

keywords = "Diagnostics, Ebola virus, Epidemic, Mobile laboratory, West Africa",

author = "{De Wit}, Emmie and Kyle Rosenke and Fischer, {Robert J.} and Andrea Marzi and Joseph Prescott and Trenton Bushmaker and {Van Doremalen}, Neeltje and Emery, {Shannon L.} and Darryl Falzarano and Friederike Feldmann and Allison Groseth and Thomas Hoenen and Bonventure Juma and McNally, {Kristin L.} and Melvin Ochieng and Victor Omballa and Onyango, {Clayton O.} and Collins Owuor and Thomas Rowe and David Safronetz and Joshua Self and Williamson, {Brandi N.} and Galina Zemtsova and Allen Grolla and Gary Kobinger and Mark Rayfield and Ute Str{\"o}her and Strong, {James E.} and Best, {Sonja M.} and Hideki Ebihara and Zoon, {Kathryn C.} and Nichol, {Stuart T.} and Nyenswah, {Tolbert G.} and Bolay, {Fatorma K.} and Moses Massaquoi and Heinz Feldmann and Barry Fields",

note = "Publisher Copyright: {\textcopyright} 2016 Published by Oxford University Press for the Infectious Diseases Society of America 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.",

year = "2016",

month = oct,

day = "15",

doi = "10.1093/infdis/jiw216",

language = "English (US)",

volume = "214",

pages = "S169--S176",

journal = "Journal of Infectious Diseases",

issn = "0022-1899",

publisher = "Oxford University Press",

}

TY - JOUR

T1 - Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015

AU - De Wit, Emmie

AU - Rosenke, Kyle

AU - Fischer, Robert J.

AU - Marzi, Andrea

AU - Prescott, Joseph

AU - Bushmaker, Trenton

AU - Van Doremalen, Neeltje

AU - Emery, Shannon L.

AU - Falzarano, Darryl

AU - Feldmann, Friederike

AU - Groseth, Allison

AU - Hoenen, Thomas

AU - Juma, Bonventure

AU - McNally, Kristin L.

AU - Ochieng, Melvin

AU - Omballa, Victor

AU - Onyango, Clayton O.

AU - Owuor, Collins

AU - Rowe, Thomas

AU - Safronetz, David

AU - Self, Joshua

AU - Williamson, Brandi N.

AU - Zemtsova, Galina

AU - Grolla, Allen

AU - Kobinger, Gary

AU - Rayfield, Mark

AU - Ströher, Ute

AU - Strong, James E.

AU - Best, Sonja M.

AU - Ebihara, Hideki

AU - Zoon, Kathryn C.

AU - Nichol, Stuart T.

AU - Nyenswah, Tolbert G.

AU - Bolay, Fatorma K.

AU - Massaquoi, Moses

AU - Feldmann, Heinz

AU - Fields, Barry

N1 - Publisher Copyright: © 2016 Published by Oxford University Press for the Infectious Diseases Society of America 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

PY - 2016/10/15

Y1 - 2016/10/15

N2 - West Africa experienced the first epidemic of Ebola virus infection, with by far the greatest number of cases in Guinea, Sierra Leone, and Liberia. The unprecedented epidemic triggered an unparalleled response, including the deployment of multiple Ebola treatment units and mobile/field diagnostic laboratories. The National Institute of Allergy and Infectious Diseases and the Centers for Disease Control and Prevention deployed a joint laboratory to Monrovia, Liberia, in August 2014 to support the newly founded Ebola treatment unit at the Eternal Love Winning Africa (ELWA) campus. The laboratory operated initially out of a tent structure but quickly moved into a fixed-wall building owing to severe weather conditions, the need for increased security, and the high sample volume. Until May 2015, when the laboratory closed, the site handled close to 6000 clinical specimens for Ebola virus diagnosis and supported the medical staff in case patient management. Laboratory operation and safety, as well as Ebola virus diagnostic assays, are described and discussed; in addition, lessons learned for future deployments are reviewed.

AB - West Africa experienced the first epidemic of Ebola virus infection, with by far the greatest number of cases in Guinea, Sierra Leone, and Liberia. The unprecedented epidemic triggered an unparalleled response, including the deployment of multiple Ebola treatment units and mobile/field diagnostic laboratories. The National Institute of Allergy and Infectious Diseases and the Centers for Disease Control and Prevention deployed a joint laboratory to Monrovia, Liberia, in August 2014 to support the newly founded Ebola treatment unit at the Eternal Love Winning Africa (ELWA) campus. The laboratory operated initially out of a tent structure but quickly moved into a fixed-wall building owing to severe weather conditions, the need for increased security, and the high sample volume. Until May 2015, when the laboratory closed, the site handled close to 6000 clinical specimens for Ebola virus diagnosis and supported the medical staff in case patient management. Laboratory operation and safety, as well as Ebola virus diagnostic assays, are described and discussed; in addition, lessons learned for future deployments are reviewed.

KW - Diagnostics

KW - Ebola virus

KW - Epidemic

KW - Mobile laboratory

KW - West Africa

UR - http://www.scopus.com/inward/record.url?scp=84990895489&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84990895489&partnerID=8YFLogxK

U2 - 10.1093/infdis/jiw216

DO - 10.1093/infdis/jiw216

M3 - Article

C2 - 27333914

AN - SCOPUS:84990895489

SN - 0022-1899

VL - 214

SP - S169-S176

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

ER -

Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this