East meets west in the search for Alzheimer's therapeutics - Novel dimeric inhibitors from tacrine and huperzine A

Medicine & Life Sciences

• 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydroacridine 100%
• huperzine A 81%
• Tacrine 63%
• Memantine 49%
• Cholinesterase Inhibitors 42%
• Alzheimer Disease 37%
• bis(12)-hupyridone 28%
• Glutamate Receptors 26%
• Neuroprotective Agents 24%
• Memory 17%
• Pharmaceutical Research 17%
• Acetylcholinesterase 13%
• N-Methylaspartate 13%
• Neurosciences 13%
• N-Methyl-D-Aspartate Receptors 12%
• Cholinergic Agents 11%
• Glutamic Acid 10%
• Neurodegenerative Diseases 10%
• Dementia 10%
• Psychological Inhibition 9%
• Animal Models 8%
• Aptitude 8%
• Therapeutics 7%
• In Vitro Techniques 5%