Abstract
Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease associated with an increased risk of colorectal cancer (CRC). Although CRC occurs in a minority of IBD patients (1%), it carries a high mortality and accounts for 20% of IBD-related mortality. Established risk factors for the development of CRC in IBD include disease duration of 8 years or more, family history of CRC, extensive colitis and primary sclerosing cholangitis. Meticulous colonoscopy and anti-inflammatory medications can reduce the risk of developing CRC. The future of IBD surveillance involves the use of novel endoscopic techniques (chromoendoscopy, narrow-band imaging, confocal laser endomicroscopy and autofluorescence) to enhance colonoscopic accuracy, in concert with chemopreventative medications to help reduce the risk of CRC in IBD.
Original language | English (US) |
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Pages (from-to) | 59-66 |
Number of pages | 8 |
Journal | Expert Review of Gastroenterology and Hepatology |
Volume | 5 |
Issue number | 1 |
DOIs | |
State | Published - Feb 2011 |
Keywords
- IBD
- colorectal cancer
- dysplasia
- inflammatory bowel disease
ASJC Scopus subject areas
- Hepatology
- Gastroenterology