Dyspepsia, irritable bowel syndrome, and constipation

review and what's new.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Functional gastrointestinal disorders are collections of symptoms attributable to the gastrointestinal tract in the absence of mucosal, structural, or biochemical disease. The two most common disorders, irritable bowel syndrome and functional dyspepsia, have common etiopathogenetic features, notably psychosocial disturbances, dysmotility, heightened sensitivity, and, possibly, an association with a postinfective state. The third condition is constipation, in which transit disorders and abnormal evacuation represent disturbances of function that are amenable to therapy. This review is an update of the control mechanisms, pathophysiology, investigation, and potential pharmacotherapies of these disorders. Serotonergic and adrenergic agents and neurotrophic factors are among the novel approaches that may have a significant impact on these disorders.

Original languageEnglish (US)
Pages (from-to)2-17
Number of pages16
JournalReviews in Gastroenterological Disorders
Volume1
Issue number1
StatePublished - 2001

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Serotonin Agents
Irritable Bowel Syndrome
Gastrointestinal Diseases
Dyspepsia
Nerve Growth Factors
Constipation
Adrenergic Agents
Gastrointestinal Tract
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Dyspepsia, irritable bowel syndrome, and constipation : review and what's new. / Camilleri, Michael.

In: Reviews in Gastroenterological Disorders, Vol. 1, No. 1, 2001, p. 2-17.

Research output: Contribution to journalArticle

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