TY - JOUR
T1 - Dynamic MR digital subtraction angiography using contrast enhancement, fast data acquisition, and complex subtraction
AU - Wang, Yi
AU - Johnston, Donald L.
AU - Breen, Jerome F.
AU - Huston, John
AU - Jack, Clifford R.
AU - Julsrud, Paul R.
AU - Kiely, Michael J.
AU - King, Bernard F.
AU - Riederer, Stephen L.
AU - Ehman, Richard L.
PY - 1996/10
Y1 - 1996/10
N2 - A dynamic MR angiography technique, MR digital subtraction angiography (MR DSA), is proposed using fast acquisition, contrast enhancement, and complex subtraction. When a bolus of contrast is injected into a patient, data acquisition begins, dynamically acquiring a thick slab using a fast gradient echo sequence for 10-100 s. Similar to x-ray DSA, a mask is selected from the images without contrast enhancement, and later images are subtracted from the mask to generate angiograms. Complex subtraction is used to overcome the partial volume effects related to the phase difference between the flowing and stationary magnetization in a voxel. Vessel signal is the enhancement of flow magnetization resulting from the contrast bolus. MR DSA was performed in 28 patients, including vessels in the lungs, brains, legs, abdomen, and pelvis. All targeted vessels were well depicted with MR DSA. Corresponding dynamic information (contrast arrival time t(a) and duration of the arterial phase t(av)) was measured: t(a)/t(av) = 3.4/4.7 s for the lung, 10.3/4.9 s for the brain, 12.8/19.3 for the aorta, 15.2/12.6 s for the leg. MR DSA can provide dynamic angiographic images using a very short acquisition time.
AB - A dynamic MR angiography technique, MR digital subtraction angiography (MR DSA), is proposed using fast acquisition, contrast enhancement, and complex subtraction. When a bolus of contrast is injected into a patient, data acquisition begins, dynamically acquiring a thick slab using a fast gradient echo sequence for 10-100 s. Similar to x-ray DSA, a mask is selected from the images without contrast enhancement, and later images are subtracted from the mask to generate angiograms. Complex subtraction is used to overcome the partial volume effects related to the phase difference between the flowing and stationary magnetization in a voxel. Vessel signal is the enhancement of flow magnetization resulting from the contrast bolus. MR DSA was performed in 28 patients, including vessels in the lungs, brains, legs, abdomen, and pelvis. All targeted vessels were well depicted with MR DSA. Corresponding dynamic information (contrast arrival time t(a) and duration of the arterial phase t(av)) was measured: t(a)/t(av) = 3.4/4.7 s for the lung, 10.3/4.9 s for the brain, 12.8/19.3 for the aorta, 15.2/12.6 s for the leg. MR DSA can provide dynamic angiographic images using a very short acquisition time.
KW - MR DSA
KW - MRA
KW - complex subtraction
KW - enhancement
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U2 - 10.1002/mrm.1910360408
DO - 10.1002/mrm.1910360408
M3 - Article
C2 - 8892206
AN - SCOPUS:10144256538
SN - 0740-3194
VL - 36
SP - 551
EP - 556
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
IS - 4
ER -