Dynamic MR digital subtraction angiography using contrast enhancement, fast data acquisition, and complex subtraction

Yi Wang, Donald L. Johnston, Jerome F. Breen, John III Huston, Clifford R Jr. Jack, Paul R. Julsrud, Michael J. Kiely, Bernard Francis King, Stephen J Riederer, Richard Lorne Ehman

Research output: Contribution to journalArticle

163 Citations (Scopus)

Abstract

A dynamic MR angiography technique, MR digital subtraction angiography (MR DSA), is proposed using fast acquisition, contrast enhancement, and complex subtraction. When a bolus of contrast is injected into a patient, data acquisition begins, dynamically acquiring a thick slab using a fast gradient echo sequence for 10-100 s. Similar to x-ray DSA, a mask is selected from the images without contrast enhancement, and later images are subtracted from the mask to generate angiograms. Complex subtraction is used to overcome the partial volume effects related to the phase difference between the flowing and stationary magnetization in a voxel. Vessel signal is the enhancement of flow magnetization resulting from the contrast bolus. MR DSA was performed in 28 patients, including vessels in the lungs, brains, legs, abdomen, and pelvis. All targeted vessels were well depicted with MR DSA. Corresponding dynamic information (contrast arrival time t(a) and duration of the arterial phase t(av)) was measured: t(a)/t(av) = 3.4/4.7 s for the lung, 10.3/4.9 s for the brain, 12.8/19.3 for the aorta, 15.2/12.6 s for the leg. MR DSA can provide dynamic angiographic images using a very short acquisition time.

Original languageEnglish (US)
Pages (from-to)551-556
Number of pages6
JournalMagnetic Resonance in Medicine
Volume36
Issue number4
StatePublished - Oct 1996

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Digital Subtraction Angiography
Masks
Leg
Angiography
Image Enhancement
Lung
Brain
Pelvis
Abdomen
Aorta
X-Rays

Keywords

  • complex subtraction
  • enhancement
  • MR DSA
  • MRA

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Dynamic MR digital subtraction angiography using contrast enhancement, fast data acquisition, and complex subtraction. / Wang, Yi; Johnston, Donald L.; Breen, Jerome F.; Huston, John III; Jack, Clifford R Jr.; Julsrud, Paul R.; Kiely, Michael J.; King, Bernard Francis; Riederer, Stephen J; Ehman, Richard Lorne.

In: Magnetic Resonance in Medicine, Vol. 36, No. 4, 10.1996, p. 551-556.

Research output: Contribution to journalArticle

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