Duodenal Crohn's disease

Amy Lightner

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Symptomatic duodenal Crohn's disease (CD) is an uncommon disease presentation, especially in isolation. The most common duodenal disease phenotype is stricturing disease rather than inflammatory or perforating. Most patients are asymptomatic and are therefore diagnosed incidentally by cross-sectional imaging or endoscopy. Medical management includes proton pump inhibitor therapy and immunosuppressive therapy including corticosteroids, immunomodulatory therapy, and biologic therapy. Symptomatic strictures can often be treated medically or endoscopically, and do not always require surgery. Surgical options include resection with primary anastomosis, bypass with a gastrojejunostomy, and strictureplasty. Treatment recommendations are largely based on limited evidence from small series and expert opinion. Therefore, the optimal treatment algorithm remains largely subjective and undefined.

Original languageEnglish (US)
Pages (from-to)546-551
Number of pages6
JournalInflammatory Bowel Diseases
Volume24
Issue number3
DOIs
StatePublished - Feb 16 2018

Fingerprint

Duodenal Diseases
Crohn Disease
Biological Therapy
Gastric Bypass
Immunomodulation
Proton Pump Inhibitors
Expert Testimony
Therapeutics
Immunosuppressive Agents
Endoscopy
Adrenal Cortex Hormones
Pathologic Constriction
Phenotype

ASJC Scopus subject areas

  • Immunology and Allergy
  • Gastroenterology

Cite this

Duodenal Crohn's disease. / Lightner, Amy.

In: Inflammatory Bowel Diseases, Vol. 24, No. 3, 16.02.2018, p. 546-551.

Research output: Contribution to journalReview article

Lightner, Amy. / Duodenal Crohn's disease. In: Inflammatory Bowel Diseases. 2018 ; Vol. 24, No. 3. pp. 546-551.
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