DTI analyses and clinical applications in Alzheimer's disease

Kenichi Oishi, Michelle M Mielke, Marilyn Albert, Constantine G. Lyketsos, Susumu Mori

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

DTI is one of the most effective MR tools for the investigation of the brain anatomy. In addition to the gray matter, histopathological studies indicate that white matter is also a good target for both the early diagnosis of AD and for monitoring disease progression, which motivates us to use DTI to study AD patients in vivo. There are already a large amount of studies reporting significant differences between AD patients and controls, as well as to predict progression of disease in symptomatic non-demented individuals. Application of these findings in clinical practice remains to be demonstrated.

Original languageEnglish (US)
Title of host publicationAdvances in Alzheimer's Disease
Pages525-534
Number of pages10
Volume2
DOIs
StatePublished - 2011
Externally publishedYes

Publication series

NameAdvances in Alzheimer's Disease
Volume2
ISSN (Print)22105727
ISSN (Electronic)22105735

Fingerprint

Disease Progression
Alzheimer Disease
Early Diagnosis
Anatomy
Brain
White Matter
Gray Matter

Keywords

  • Alzheimer's disease
  • clinical application
  • diffusion tensor imaging
  • mild cognitive impairment
  • white matter

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Oishi, K., Mielke, M. M., Albert, M., Lyketsos, C. G., & Mori, S. (2011). DTI analyses and clinical applications in Alzheimer's disease. In Advances in Alzheimer's Disease (Vol. 2, pp. 525-534). (Advances in Alzheimer's Disease; Vol. 2). https://doi.org/10.3233/978-1-60750-793-2-525

DTI analyses and clinical applications in Alzheimer's disease. / Oishi, Kenichi; Mielke, Michelle M; Albert, Marilyn; Lyketsos, Constantine G.; Mori, Susumu.

Advances in Alzheimer's Disease. Vol. 2 2011. p. 525-534 (Advances in Alzheimer's Disease; Vol. 2).

Research output: Chapter in Book/Report/Conference proceedingChapter

Oishi, K, Mielke, MM, Albert, M, Lyketsos, CG & Mori, S 2011, DTI analyses and clinical applications in Alzheimer's disease. in Advances in Alzheimer's Disease. vol. 2, Advances in Alzheimer's Disease, vol. 2, pp. 525-534. https://doi.org/10.3233/978-1-60750-793-2-525
Oishi K, Mielke MM, Albert M, Lyketsos CG, Mori S. DTI analyses and clinical applications in Alzheimer's disease. In Advances in Alzheimer's Disease. Vol. 2. 2011. p. 525-534. (Advances in Alzheimer's Disease). https://doi.org/10.3233/978-1-60750-793-2-525
Oishi, Kenichi ; Mielke, Michelle M ; Albert, Marilyn ; Lyketsos, Constantine G. ; Mori, Susumu. / DTI analyses and clinical applications in Alzheimer's disease. Advances in Alzheimer's Disease. Vol. 2 2011. pp. 525-534 (Advances in Alzheimer's Disease).
@inbook{db7343c117c14f908cffb1aed92f3079,
title = "DTI analyses and clinical applications in Alzheimer's disease",
abstract = "DTI is one of the most effective MR tools for the investigation of the brain anatomy. In addition to the gray matter, histopathological studies indicate that white matter is also a good target for both the early diagnosis of AD and for monitoring disease progression, which motivates us to use DTI to study AD patients in vivo. There are already a large amount of studies reporting significant differences between AD patients and controls, as well as to predict progression of disease in symptomatic non-demented individuals. Application of these findings in clinical practice remains to be demonstrated.",
keywords = "Alzheimer's disease, clinical application, diffusion tensor imaging, mild cognitive impairment, white matter",
author = "Kenichi Oishi and Mielke, {Michelle M} and Marilyn Albert and Lyketsos, {Constantine G.} and Susumu Mori",
year = "2011",
doi = "10.3233/978-1-60750-793-2-525",
language = "English (US)",
isbn = "9781607507925",
volume = "2",
series = "Advances in Alzheimer's Disease",
pages = "525--534",
booktitle = "Advances in Alzheimer's Disease",

}

TY - CHAP

T1 - DTI analyses and clinical applications in Alzheimer's disease

AU - Oishi, Kenichi

AU - Mielke, Michelle M

AU - Albert, Marilyn

AU - Lyketsos, Constantine G.

AU - Mori, Susumu

PY - 2011

Y1 - 2011

N2 - DTI is one of the most effective MR tools for the investigation of the brain anatomy. In addition to the gray matter, histopathological studies indicate that white matter is also a good target for both the early diagnosis of AD and for monitoring disease progression, which motivates us to use DTI to study AD patients in vivo. There are already a large amount of studies reporting significant differences between AD patients and controls, as well as to predict progression of disease in symptomatic non-demented individuals. Application of these findings in clinical practice remains to be demonstrated.

AB - DTI is one of the most effective MR tools for the investigation of the brain anatomy. In addition to the gray matter, histopathological studies indicate that white matter is also a good target for both the early diagnosis of AD and for monitoring disease progression, which motivates us to use DTI to study AD patients in vivo. There are already a large amount of studies reporting significant differences between AD patients and controls, as well as to predict progression of disease in symptomatic non-demented individuals. Application of these findings in clinical practice remains to be demonstrated.

KW - Alzheimer's disease

KW - clinical application

KW - diffusion tensor imaging

KW - mild cognitive impairment

KW - white matter

UR - http://www.scopus.com/inward/record.url?scp=84555160716&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84555160716&partnerID=8YFLogxK

U2 - 10.3233/978-1-60750-793-2-525

DO - 10.3233/978-1-60750-793-2-525

M3 - Chapter

AN - SCOPUS:84555160716

SN - 9781607507925

VL - 2

T3 - Advances in Alzheimer's Disease

SP - 525

EP - 534

BT - Advances in Alzheimer's Disease

ER -