DTI analyses and clinical applications in Alzheimer's disease

Kenichi Oishi, Michelle M. Mielke, Marilyn Albert, Constantine G. Lyketsos, Susumu Mori

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Abstract

DTI is one of the most effective MR tools for the investigation of the brain anatomy. In addition to the gray matter, histopathological studies indicate that white matter is also a good target for both the early diagnosis of AD and for monitoring disease progression, which motivates us to use DTI to study AD patients in vivo. There are already a large amount of studies reporting significant differences between AD patients and controls, as well as to predict progression of disease in symptomatic non-demented individuals. Application of these findings in clinical practice remains to be demonstrated.

Original languageEnglish (US)
Title of host publicationHandbook of Imaging the Alzheimer Brain
EditorsJ. Wesson Ashford, Allyson Rosen, Maheen Adamson, Peter Bayley, Ansgar Furst, Osama Sabri, Sandra E. Black, Michael Weiner
Pages525-534
Number of pages10
DOIs
StatePublished - Dec 1 2011

Publication series

NameAdvances in Alzheimer's Disease
Volume2
ISSN (Print)2210-5727
ISSN (Electronic)2210-5735

Keywords

  • Alzheimer's disease
  • clinical application
  • diffusion tensor imaging
  • mild cognitive impairment
  • white matter

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'DTI analyses and clinical applications in Alzheimer's disease'. Together they form a unique fingerprint.

  • Cite this

    Oishi, K., Mielke, M. M., Albert, M., Lyketsos, C. G., & Mori, S. (2011). DTI analyses and clinical applications in Alzheimer's disease. In J. Wesson Ashford, A. Rosen, M. Adamson, P. Bayley, A. Furst, O. Sabri, S. E. Black, & M. Weiner (Eds.), Handbook of Imaging the Alzheimer Brain (pp. 525-534). (Advances in Alzheimer's Disease; Vol. 2). https://doi.org/10.3233/978-1-60750-793-2-525