Dravet Syndrome as an Example of Precision Medicine in Epilepsy

Joseph Sullivan, Elaine C. Wirrell

Research output: Contribution to journalReview articlepeer-review


Dravet syndrome (DS) is a drug-resistant, early-onset, developmental and epileptic encephalopathy where there have been many recently approved therapies with many more in development. With the availability of more syndrome specific treatment options coupled with an earlier diagnosis, DS is well-positioned to be an example of how a precise syndromic diagnosis can guide treatment choices and improve overall outcomes and also allow for the development of potential disease modifying therapies to address more than just seizures. In this review we summarize the current state of DS approved therapies and those that are in various stages of development.

Original languageEnglish (US)
Pages (from-to)4-7
Number of pages4
JournalEpilepsy Currents
Issue number1
StatePublished - Jan 1 2023


  • Dravet
  • anti seizure medication
  • developmental epileptic encephalopathy
  • disease modifying therapy
  • epilepsy syndrome
  • precision medicine

ASJC Scopus subject areas

  • Clinical Neurology


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