Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death of osteosarcoma cells

Medicine & Life Sciences

• 2-Methoxyestradiol 100%
• eIF-2 Kinase 90%
• Double-Stranded RNA 76%
• Osteosarcoma 66%
• Cell Death 48%
• Interferons 20%
• Eukaryotic Initiation Factor-2 13%
• Phosphorylation 9%
• Proteins 8%
• 4-hydroxyestradiol 8%
• Estradiol 7%
• 2-Aminopurine 7%
• Poly C 6%
• Poly I-C 5%
• SB 203580 5%
• Apoptosis 5%
• Gene Expression 5%
• Trypan Blue 5%
• Protein-Serine-Threonine Kinases 5%
• Mutant Proteins 4%
• Transfection 3%
• Coloring Agents 3%
• Phosphotransferases 3%
• Western Blotting 3%
• Bone and Bones 2%
• Therapeutics 1%
• Neoplasms 1%