Dopamine agonist therapy for Parkinson disease and pathological gambling

Akiko Imamura; Ryan J. Uitti; Zbigniew K. Wszolek

doi:10.1016/j.parkreldis.2006.02.004

Dopamine agonist therapy for Parkinson disease and pathological gambling

Akiko Imamura, Ryan J. Uitti, Zbigniew K. Wszolek

Neurology

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

We report 6 patients with pathological gambling during pharmacologic treatment for Parkinson disease (PD). Four patients were treated with levodopa/carbidopa and dopamine agonist (DA), and 2 patients received DA monotherapy. We reviewed several published reports regarding pathological gambling and antiparkinsonian therapy and suggest that more advanced PD and antiparkinsonian combination therapy (e.g., levodopa/carbidopa and DA) increases the risk for development of pathological gambling behavior compared with monotherapy with either DA or levodopa/carbidopa.

Original language	English (US)
Pages (from-to)	506-508
Number of pages	3
Journal	Parkinsonism and Related Disorders
Volume	12
Issue number	8
DOIs	https://doi.org/10.1016/j.parkreldis.2006.02.004
State	Published - Dec 2006

Keywords

Dopamine agonist
Levodopa
Parkinson disease
Pathological gambling

ASJC Scopus subject areas

Neurology
Geriatrics and Gerontology
Clinical Neurology

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10.1016/j.parkreldis.2006.02.004

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AB - We report 6 patients with pathological gambling during pharmacologic treatment for Parkinson disease (PD). Four patients were treated with levodopa/carbidopa and dopamine agonist (DA), and 2 patients received DA monotherapy. We reviewed several published reports regarding pathological gambling and antiparkinsonian therapy and suggest that more advanced PD and antiparkinsonian combination therapy (e.g., levodopa/carbidopa and DA) increases the risk for development of pathological gambling behavior compared with monotherapy with either DA or levodopa/carbidopa.

KW - Dopamine agonist

KW - Levodopa

KW - Parkinson disease

KW - Pathological gambling

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Dopamine agonist therapy for Parkinson disease and pathological gambling

Abstract

Keywords

ASJC Scopus subject areas

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