Does Implantation of Sonomicrometry Crystals Alter Regional Cardiac Muscle Function?

Josef Korinek, Jan Vitek, Partho P. Sengupta, Abel Romero-Corral, Vijay K. Krishnamoorthy, Eileen M. McMahon, Bijoy K. Khandheria, Marek Belohlavek

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Sonomicrometry is a gold standard in experimental studies on myocardial motion. However, limited information exists regarding mechanical and biochemical changes produced by sonomicrometry crystal (SC) insertion into the myocardial wall. Methods: In 10 open-chest pigs, we implanted SCs into the inner half of apical anterior and midposterior regions. Longitudinal strains (systolic lengthening, end-systolic, peak shortening, and postsystolic shortening strains) and strain rate (SR) measurements (peak systolic ejection and early and late diastolic SRs) were obtained by Doppler SR echocardiography along with troponin I levels measured from peripheral blood before and after SC insertion. Results: SR and strain parameters did not change significantly after SC implantation. Troponin I levels increased significantly from less than 0.010 to 0.129 ± 0.138 μg/L (P < .005) after SC implantation. Conclusions: Our study demonstrates that despite biochemical evidence of myocardial injury, carefully implanted SCs do not alter systolic or diastolic regional myocardial function assessed by Doppler echocardiography.

Original languageEnglish (US)
Pages (from-to)1407-1412
Number of pages6
JournalJournal of the American Society of Echocardiography
Volume20
Issue number12
DOIs
StatePublished - Dec 2007

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Troponin I
Myocardium
Doppler Echocardiography
Echocardiography
Swine
Thorax
Wounds and Injuries

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Does Implantation of Sonomicrometry Crystals Alter Regional Cardiac Muscle Function? / Korinek, Josef; Vitek, Jan; Sengupta, Partho P.; Romero-Corral, Abel; Krishnamoorthy, Vijay K.; McMahon, Eileen M.; Khandheria, Bijoy K.; Belohlavek, Marek.

In: Journal of the American Society of Echocardiography, Vol. 20, No. 12, 12.2007, p. 1407-1412.

Research output: Contribution to journalArticle

Korinek, J, Vitek, J, Sengupta, PP, Romero-Corral, A, Krishnamoorthy, VK, McMahon, EM, Khandheria, BK & Belohlavek, M 2007, 'Does Implantation of Sonomicrometry Crystals Alter Regional Cardiac Muscle Function?', Journal of the American Society of Echocardiography, vol. 20, no. 12, pp. 1407-1412. https://doi.org/10.1016/j.echo.2007.04.010
Korinek, Josef ; Vitek, Jan ; Sengupta, Partho P. ; Romero-Corral, Abel ; Krishnamoorthy, Vijay K. ; McMahon, Eileen M. ; Khandheria, Bijoy K. ; Belohlavek, Marek. / Does Implantation of Sonomicrometry Crystals Alter Regional Cardiac Muscle Function?. In: Journal of the American Society of Echocardiography. 2007 ; Vol. 20, No. 12. pp. 1407-1412.
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AU - Sengupta, Partho P.

AU - Romero-Corral, Abel

AU - Krishnamoorthy, Vijay K.

AU - McMahon, Eileen M.

AU - Khandheria, Bijoy K.

AU - Belohlavek, Marek

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AB - Background: Sonomicrometry is a gold standard in experimental studies on myocardial motion. However, limited information exists regarding mechanical and biochemical changes produced by sonomicrometry crystal (SC) insertion into the myocardial wall. Methods: In 10 open-chest pigs, we implanted SCs into the inner half of apical anterior and midposterior regions. Longitudinal strains (systolic lengthening, end-systolic, peak shortening, and postsystolic shortening strains) and strain rate (SR) measurements (peak systolic ejection and early and late diastolic SRs) were obtained by Doppler SR echocardiography along with troponin I levels measured from peripheral blood before and after SC insertion. Results: SR and strain parameters did not change significantly after SC implantation. Troponin I levels increased significantly from less than 0.010 to 0.129 ± 0.138 μg/L (P < .005) after SC implantation. Conclusions: Our study demonstrates that despite biochemical evidence of myocardial injury, carefully implanted SCs do not alter systolic or diastolic regional myocardial function assessed by Doppler echocardiography.

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