Dobutamine stress echocardiography in the detection of coronary artery disease: Importance of the pretest likelihood of disease

T. G. Hennessy, M. B. Codd, G. Kane, C. McCarthy, H. A. McCann, D. D. Sugrue

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Although the accuracy of dobutamine stress echocardiography far the detection of coronary artery disease in a high-risk population is known, it has not been well defined for lower risk groups. Two probability groups, high (>75%; n = 199) and intermediate (>10% but ≤75%; n = 118), were studied. Dobutamine stress echocardiography was performed in a standard fashion. Significant coronary artery disease was defined as o >50% luminal diameter stenosis on coronary angiography. The positive predictive accuracy of dobutamine stress echocardiography for the detection of coronary artery disease was greater in the high-probability group (96% vs 86%), as was the sensitivity (89% vs 78%), whereas the negative predictive value was greater in the intermediate-probability group (50% vs 23%), as was the specificity (63% vs 50%). Dobutamine stress echocardiography does have a diagnostic role in the evaluation of patients with an intermediate probability of coronary artery disease.

Original languageEnglish (US)
Pages (from-to)685-692
Number of pages8
JournalAmerican heart journal
Volume134
Issue number4
DOIs
StatePublished - Jan 1 1997

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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