DNA marker d11s384 shows zero recombination with the ataxia-telangiectasia locus in north american families

N. J. Lench; P. Athma; A. Ottaiano; W. M. Sribney; E. Highsmith; M. Swift

doi:10.1080/09553009414551881

DNA marker d11s384 shows zero recombination with the ataxia-telangiectasia locus in north american families

N. J. Lench, P. Athma, A. Ottaiano, W. M. Sribney, E. Highsmith, M. Swift

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

At the genetic locus D11S384, one probe detects a Taq1 RFLP and another detects a RFMP. In 52 pedigrees of North American A-T patients, parental haplotypes based on these two bi-allelic systems have a heterozygosity of 0.69 and a PIC of 0.64. No recombinant events between D11S384 and the A-T locus were detected in the 43 pedigrees in which this marker locus was informative.

Original language	English (US)
Pages (from-to)	S67-S69
Journal	International Journal of Radiation Biology
Volume	66
Issue number	6
DOIs	https://doi.org/10.1080/09553009414551881
State	Published - 1994

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

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title = "DNA marker d11s384 shows zero recombination with the ataxia-telangiectasia locus in north american families",

abstract = "At the genetic locus D11S384, one probe detects a Taq1 RFLP and another detects a RFMP. In 52 pedigrees of North American A-T patients, parental haplotypes based on these two bi-allelic systems have a heterozygosity of 0.69 and a PIC of 0.64. No recombinant events between D11S384 and the A-T locus were detected in the 43 pedigrees in which this marker locus was informative.",

author = "Lench, {N. J.} and P. Athma and A. Ottaiano and Sribney, {W. M.} and E. Highsmith and M. Swift",

note = "Funding Information: We thank C . Julier for providing probe CJ52 .193, M . Smith for CJ52 .193 DNA sequence data, Jie Wu for technical assistance, and J . Ott for supplying the LINKAGE programs . This work was supported by NIH Grants CA14235 and 50489 .",

year = "1994",

doi = "10.1080/09553009414551881",

language = "English (US)",

volume = "66",

pages = "S67--S69",

journal = "International Journal of Radiation Biology",

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TY - JOUR

T1 - DNA marker d11s384 shows zero recombination with the ataxia-telangiectasia locus in north american families

AU - Lench, N. J.

AU - Athma, P.

AU - Ottaiano, A.

AU - Sribney, W. M.

AU - Highsmith, E.

AU - Swift, M.

N1 - Funding Information: We thank C . Julier for providing probe CJ52 .193, M . Smith for CJ52 .193 DNA sequence data, Jie Wu for technical assistance, and J . Ott for supplying the LINKAGE programs . This work was supported by NIH Grants CA14235 and 50489 .

PY - 1994

Y1 - 1994

N2 - At the genetic locus D11S384, one probe detects a Taq1 RFLP and another detects a RFMP. In 52 pedigrees of North American A-T patients, parental haplotypes based on these two bi-allelic systems have a heterozygosity of 0.69 and a PIC of 0.64. No recombinant events between D11S384 and the A-T locus were detected in the 43 pedigrees in which this marker locus was informative.

AB - At the genetic locus D11S384, one probe detects a Taq1 RFLP and another detects a RFMP. In 52 pedigrees of North American A-T patients, parental haplotypes based on these two bi-allelic systems have a heterozygosity of 0.69 and a PIC of 0.64. No recombinant events between D11S384 and the A-T locus were detected in the 43 pedigrees in which this marker locus was informative.

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DNA marker d11s384 shows zero recombination with the ataxia-telangiectasia locus in north american families

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