Diuretic renal scintigraphy in patients with sulfonamide allergies: Possible alternative use of ethacrynic acid

Ba D. Nguyen, Michael C. Roarke, Jason Robert Young, Ming Yang, Howard H. Osborn

Research output: Contribution to journalArticle

Abstract

Furosemide may trigger life-threatening sulfonamide crosshypersensitivity reactions, posing a dilemma in patients who need diuretic renal scintigraphy. Methods: We present our experience using ethacrynic acid as a nonsulfonamide alternative diuretic in 5 patients, with a discussion of the diuretic molecular structure, potential side effects, protocol development, and imaging results. Results: Diuretic renal scintigraphy using ethacrynic acid provided useful information about the obstruction status in all patients, with no adverse clinical impact. Conclusion: Ethacrynic acid is a potential alternative to furosemide for patients with severe sulfonamide reactions.

Original languageEnglish (US)
Pages (from-to)239-241
Number of pages3
JournalJournal of nuclear medicine technology
Volume43
Issue number4
DOIs
StatePublished - 2015

Keywords

  • Diuretic renal scintigraphy
  • Ethacrynic acid
  • Sulfonamide allergy

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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