TY - JOUR
T1 - Distribution of neuromedin U-like immunoreactivity in the central nervous system of Rana esculenta
AU - Maderdrut, Jerome L.
AU - Lázár, Gyula
AU - Kozicz, Tamás
AU - Merchenthaler, István
N1 - Funding Information:
Nurses from several occupational health centers in central and southeastern Sweden generously assisted the authors during the field phase of the study, and Ing-Liss Bryngelsson helped with data rnan-agement. The analyses of E-URO-D were performed by Ann Henrich-son. We are also indebted to Dr. Olav Axelson for comments on the manuscript. , Financial support was obtained from the Orebro County Council (grant no. 632-92).
PY - 1996
Y1 - 1996
N2 - The distribution of perikarya and nerve fibers containing neuromedin U- like immunoreactivity in the brain of Rana esculenta was determined with an antiserum directed toward the carboxyl terminus of the peptide. In the telencephalon, immunoreactive perikarya were found in the olfactory bulb, the medial septum, and the diagonal band. In the diencephalon, labeled perikarya were detected in the anterior and posterior preoptic areas, the dorsal nucleus of the hypothalamus, the caudal part of the infundibulum, and the posterior tuberculum. In the mesencephalon, immunoreactive cell bodies were found only in the laminar nucleus of the torus semicircularis and the anterodorsal tegmental nucleus. In the rhombencephalon, labeled perikarya were detected in the secondary visceral nucleus, the cerebellar nucleus, the central gray, and the nucleus of the solitary tract. Immunoreactive nerve fibers were observed in all areas of the brain that contained labeled perikarya. The densest accumulations were found in the nucleus accumbens; the dorsal part of the lateral septum; the periventricular region of the ventral thalamus; the lateral part of the infundibulum; the anterodorsal, anteroventral, posterodorsal, and posteroventral tegmental nuclei; and the periaqueductal region of the tegmentum. The distribution of neuromedin U- like immunoreactivity in the frog brain was substantially different from the distribution described for the rodent brain.
AB - The distribution of perikarya and nerve fibers containing neuromedin U- like immunoreactivity in the brain of Rana esculenta was determined with an antiserum directed toward the carboxyl terminus of the peptide. In the telencephalon, immunoreactive perikarya were found in the olfactory bulb, the medial septum, and the diagonal band. In the diencephalon, labeled perikarya were detected in the anterior and posterior preoptic areas, the dorsal nucleus of the hypothalamus, the caudal part of the infundibulum, and the posterior tuberculum. In the mesencephalon, immunoreactive cell bodies were found only in the laminar nucleus of the torus semicircularis and the anterodorsal tegmental nucleus. In the rhombencephalon, labeled perikarya were detected in the secondary visceral nucleus, the cerebellar nucleus, the central gray, and the nucleus of the solitary tract. Immunoreactive nerve fibers were observed in all areas of the brain that contained labeled perikarya. The densest accumulations were found in the nucleus accumbens; the dorsal part of the lateral septum; the periventricular region of the ventral thalamus; the lateral part of the infundibulum; the anterodorsal, anteroventral, posterodorsal, and posteroventral tegmental nuclei; and the periaqueductal region of the tegmentum. The distribution of neuromedin U- like immunoreactivity in the frog brain was substantially different from the distribution described for the rodent brain.
KW - Amphibia
KW - evolution
KW - hypothalamus
KW - immunocytochemistry
KW - peptides
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U2 - 10.1002/(SICI)1096-9861(19960603)369:3<438::AID-CNE8>3.0.CO;2-6
DO - 10.1002/(SICI)1096-9861(19960603)369:3<438::AID-CNE8>3.0.CO;2-6
M3 - Article
C2 - 8743423
AN - SCOPUS:0029996971
SN - 0021-9967
VL - 369
SP - 438
EP - 450
JO - Journal of Comparative Neurology
JF - Journal of Comparative Neurology
IS - 3
ER -