Distribution of HLA antigens in Indian Gurkha population

T. K. Chaudhuri, T. K. Mandal, T. K. Sen, V. Taneja

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Fifty unrelated Indian Gurkha of Nepalese origin were studied to analyse the HLA antigen profile and their relation with other populations. Haplotype B35-Cw4 occurred with highest incidence and significant positive linkage disequilibrium in Gurkhas. Haplotype A10-B8 which occurs with the highest frequency in north Indians was also observed to occur with significant positive linkage in Gurkhas. HLA profile of Gurkhas thus may be the result of long term isolation and genetic drift.

Original languageEnglish (US)
Pages (from-to)170-172
Number of pages3
JournalIndian Journal of Medical Research
Volume101
Issue numberAPR.
StatePublished - Jan 1 1995

Keywords

  • Gurkha
  • HLA antigen
  • Haplotype
  • Phenotype

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Chaudhuri, T. K., Mandal, T. K., Sen, T. K., & Taneja, V. (1995). Distribution of HLA antigens in Indian Gurkha population. Indian Journal of Medical Research, 101(APR.), 170-172.