Abstract
Fifty unrelated Indian Gurkha of Nepalese origin were studied to analyse the HLA antigen profile and their relation with other populations. Haplotype B35-Cw4 occurred with highest incidence and significant positive linkage disequilibrium in Gurkhas. Haplotype A10-B8 which occurs with the highest frequency in north Indians was also observed to occur with significant positive linkage in Gurkhas. HLA profile of Gurkhas thus may be the result of long term isolation and genetic drift.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 170-172 |
| Number of pages | 3 |
| Journal | Indian Journal of Medical Research |
| Volume | 101 |
| Issue number | APR. |
| State | Published - 1995 |
Keywords
- Gurkha
- HLA antigen
- Haplotype
- Phenotype
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology