Distribution of HLA antigens in Indian Gurkha population

T. K. Chaudhuri, T. K. Mandal, T. K. Sen, Veena D Taneja

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Fifty unrelated Indian Gurkha of Nepalese origin were studied to analyse the HLA antigen profile and their relation with other populations. Haplotype B35-Cw4 occurred with highest incidence and significant positive linkage disequilibrium in Gurkhas. Haplotype A10-B8 which occurs with the highest frequency in north Indians was also observed to occur with significant positive linkage in Gurkhas. HLA profile of Gurkhas thus may be the result of long term isolation and genetic drift.

Original languageEnglish (US)
Pages (from-to)170-172
Number of pages3
JournalIndian Journal of Medical Research
Volume101
Issue numberAPR.
StatePublished - 1995
Externally publishedYes

Fingerprint

HLA Antigens
Haplotypes
Genetic Drift
antineoplaston A10
Linkage Disequilibrium
Population
Incidence

Keywords

  • Gurkha
  • Haplotype
  • HLA antigen
  • Phenotype

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Chaudhuri, T. K., Mandal, T. K., Sen, T. K., & Taneja, V. D. (1995). Distribution of HLA antigens in Indian Gurkha population. Indian Journal of Medical Research, 101(APR.), 170-172.

Distribution of HLA antigens in Indian Gurkha population. / Chaudhuri, T. K.; Mandal, T. K.; Sen, T. K.; Taneja, Veena D.

In: Indian Journal of Medical Research, Vol. 101, No. APR., 1995, p. 170-172.

Research output: Contribution to journalArticle

Chaudhuri, TK, Mandal, TK, Sen, TK & Taneja, VD 1995, 'Distribution of HLA antigens in Indian Gurkha population', Indian Journal of Medical Research, vol. 101, no. APR., pp. 170-172.
Chaudhuri, T. K. ; Mandal, T. K. ; Sen, T. K. ; Taneja, Veena D. / Distribution of HLA antigens in Indian Gurkha population. In: Indian Journal of Medical Research. 1995 ; Vol. 101, No. APR. pp. 170-172.
@article{f70b12ba13b6453b99d4c397b0b4cbe6,
title = "Distribution of HLA antigens in Indian Gurkha population",
abstract = "Fifty unrelated Indian Gurkha of Nepalese origin were studied to analyse the HLA antigen profile and their relation with other populations. Haplotype B35-Cw4 occurred with highest incidence and significant positive linkage disequilibrium in Gurkhas. Haplotype A10-B8 which occurs with the highest frequency in north Indians was also observed to occur with significant positive linkage in Gurkhas. HLA profile of Gurkhas thus may be the result of long term isolation and genetic drift.",
keywords = "Gurkha, Haplotype, HLA antigen, Phenotype",
author = "Chaudhuri, {T. K.} and Mandal, {T. K.} and Sen, {T. K.} and Taneja, {Veena D}",
year = "1995",
language = "English (US)",
volume = "101",
pages = "170--172",
journal = "Indian Journal of Medical Research",
issn = "0971-5916",
publisher = "Indian Council of Medical Research",
number = "APR.",

}

TY - JOUR

T1 - Distribution of HLA antigens in Indian Gurkha population

AU - Chaudhuri, T. K.

AU - Mandal, T. K.

AU - Sen, T. K.

AU - Taneja, Veena D

PY - 1995

Y1 - 1995

N2 - Fifty unrelated Indian Gurkha of Nepalese origin were studied to analyse the HLA antigen profile and their relation with other populations. Haplotype B35-Cw4 occurred with highest incidence and significant positive linkage disequilibrium in Gurkhas. Haplotype A10-B8 which occurs with the highest frequency in north Indians was also observed to occur with significant positive linkage in Gurkhas. HLA profile of Gurkhas thus may be the result of long term isolation and genetic drift.

AB - Fifty unrelated Indian Gurkha of Nepalese origin were studied to analyse the HLA antigen profile and their relation with other populations. Haplotype B35-Cw4 occurred with highest incidence and significant positive linkage disequilibrium in Gurkhas. Haplotype A10-B8 which occurs with the highest frequency in north Indians was also observed to occur with significant positive linkage in Gurkhas. HLA profile of Gurkhas thus may be the result of long term isolation and genetic drift.

KW - Gurkha

KW - Haplotype

KW - HLA antigen

KW - Phenotype

UR - http://www.scopus.com/inward/record.url?scp=0028942527&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028942527&partnerID=8YFLogxK

M3 - Article

VL - 101

SP - 170

EP - 172

JO - Indian Journal of Medical Research

JF - Indian Journal of Medical Research

SN - 0971-5916

IS - APR.

ER -