Distribution of HLA antigens in a sample of the North Indian Hindu population

N. K. Mehra; V. Taneja; S. Kailash; N. Raizada; M. C. Vaidya

doi:10.1111/j.1399-0039.1986.tb01500.x

Distribution of HLA antigens in a sample of the North Indian Hindu population

N. K. Mehra, V. Taneja, S. Kailash, N. Raizada, M. C. Vaidya

Immunology

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

The Indian population can be divided broadly into Dravidians and the Aryans. In this report, we have attempted to analyze the HLA genetic profile of 400 native North Indian Hindus of Aryan descent. The gene frequencies of a majority of class I and II antigens show similarity to the Caucasoid population. An interesting finding was a complete lack of antigen B14 while B16 and B41 occurred with the least frequency. Haplotype A10, B8 with significant positive linkage disequilibrium as well as showing the highest incidence is characteristic of North Indians.

Original language	English (US)
Pages (from-to)	64-74
Number of pages	11
Journal	Tissue Antigens
Volume	27
Issue number	2
DOIs	https://doi.org/10.1111/j.1399-0039.1986.tb01500.x
State	Published - Feb 1986

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Biochemistry
Genetics

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AU - Raizada, N.

AU - Vaidya, M. C.

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AB - The Indian population can be divided broadly into Dravidians and the Aryans. In this report, we have attempted to analyze the HLA genetic profile of 400 native North Indian Hindus of Aryan descent. The gene frequencies of a majority of class I and II antigens show similarity to the Caucasoid population. An interesting finding was a complete lack of antigen B14 while B16 and B41 occurred with the least frequency. Haplotype A10, B8 with significant positive linkage disequilibrium as well as showing the highest incidence is characteristic of North Indians.

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Distribution of HLA antigens in a sample of the North Indian Hindu population

Abstract

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