Distance from construction site and risk for coccidioidomycosis, Arizona, USA

Janis E. Blair, Yu Hui H Chang, Yvette Ruiz, Stacy Duffy, Beth E. Heinrich, Douglas F. Lake

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Coccidioides spp. fungi, which are present in soil in the southwestern United States, can become airborne when the soil is disrupted, and humans who inhale the spores can become infected. In 2012, our institution in Maricopa County, Arizona, USA, began a building project requiring extensive excavation of soil. One year after construction began, we compared the acquisition of coccidioidomycosis in employees working adjacent to the construction site (campus A) with that of employees working 13 miles away (campus B). Initial testing indicated prior occult coccidioidal infection in 20 (11.4%) of 176 campus A employees and in 19 (13.6%) of 140 campus B employees (p = 0.55). At the 1-year followup, 3 (2.5%) of 120 employees from campus A and 8 (8.9%) of 90 from campus B had flow cytometric evidence of new coccidioidal infection (p = 0.04). The rate of coccidioidal acquisition differed significantly between campuses, but was not higher on the campus with construction.

Original languageEnglish (US)
Pages (from-to)1464-1471
Number of pages8
JournalEmerging Infectious Diseases
Volume20
Issue number9
DOIs
StatePublished - 2014

Fingerprint

Coccidioidomycosis
Soil
Southwestern United States
Coccidioides
Infection
Spores
Fungi

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Epidemiology

Cite this

Blair, J. E., Chang, Y. H. H., Ruiz, Y., Duffy, S., Heinrich, B. E., & Lake, D. F. (2014). Distance from construction site and risk for coccidioidomycosis, Arizona, USA. Emerging Infectious Diseases, 20(9), 1464-1471. https://doi.org/10.3201/eid2009.131588

Distance from construction site and risk for coccidioidomycosis, Arizona, USA. / Blair, Janis E.; Chang, Yu Hui H; Ruiz, Yvette; Duffy, Stacy; Heinrich, Beth E.; Lake, Douglas F.

In: Emerging Infectious Diseases, Vol. 20, No. 9, 2014, p. 1464-1471.

Research output: Contribution to journalArticle

Blair, JE, Chang, YHH, Ruiz, Y, Duffy, S, Heinrich, BE & Lake, DF 2014, 'Distance from construction site and risk for coccidioidomycosis, Arizona, USA', Emerging Infectious Diseases, vol. 20, no. 9, pp. 1464-1471. https://doi.org/10.3201/eid2009.131588
Blair, Janis E. ; Chang, Yu Hui H ; Ruiz, Yvette ; Duffy, Stacy ; Heinrich, Beth E. ; Lake, Douglas F. / Distance from construction site and risk for coccidioidomycosis, Arizona, USA. In: Emerging Infectious Diseases. 2014 ; Vol. 20, No. 9. pp. 1464-1471.
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