Disparities in Surgical Care among Women with Endometrial Cancer

Diana Mannschreck, Rayna K. Matsuno, James P. Moriarty, Bijan J Borah, Sean Christopher Dowdy, Edward J. Tanner, Martin A. Makary, Rebecca L. Stone, Kimberly L. Levinson, Sarah M. Temkin, Amanda N. Fader

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

OBJECTIVE: To analyze contemporary U.S. use of minimally invasive surgery for the treatment of endometrial cancer and associated inpatient complications and costs. METHODS: In this retrospective cohort study, the National Inpatient Sample database was analyzed in patients with nonmetastatic endometrial cancer who underwent hysterectomy during 2012-2013. Hierarchical multiple logistic regression and propensity score matching were used to compare complications among patients treated with open compared with minimally invasive hysterectomy surgery. Cost of care was also compared using generalized linear modeling. RESULTS: We identified 9,799 patients; 52.4% underwent open and 47.6% minimally invasive hysterectomy. Many patients (43.4%) were treated at low-volume hospitals (less than 10 endometrial cancer cases annually). Patients were less likely to undergo open surgery in high-volume compared with low-volume hospitals (51.8% compared with 58.1%, respectively; adjusted odds ratio [OR] 0.35, 95% confidence interval [CI] 0.13-0.94) and more likely to undergo open surgery in rural compared with urban teaching hospitals (75.6% compared with 51.1%, respectively; adjusted OR 14.34, 95% CI 9.66-21.27), government compared with nonprofit hospitals (61.3% compared with 51.1%, respectively; adjusted OR 1.66, 95% CI 1.15-2.39), and in patients of black (67.9%; OR 1.46, 95% CI 1.30-1.65) and "other" race (60.5%; adjusted OR 2.39, 95% CI 1.99-2.87) compared with white race (49.2%, referent). Open surgery was associated with increased perioperative complications (adjusted OR 2.80, 95% CI 2.48-3.17) and a $1,243 increase in cost per case compared with minimally invasive approaches (P<.001). Using minimally invasive surgery for 80% of study patients may have averted 2,733 complications and saved approximately $19 million. CONCLUSION: Most U.S. women with endometrial cancer continue to be treated with open hysterectomy surgery despite increased complication rates and financial costs associated with this approach. A disparity in endometrial cancer surgical care exists that is affected by patient race and hospital geography and cancer volumes.

Original languageEnglish (US)
Pages (from-to)526-534
Number of pages9
JournalObstetrics and Gynecology
Volume128
Issue number3
DOIs
StatePublished - Sep 1 2016

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Endometrial Neoplasms
Odds Ratio
Confidence Intervals
Hysterectomy
Minimally Invasive Surgical Procedures
Low-Volume Hospitals
Costs and Cost Analysis
Inpatients
Cancer Care Facilities
Propensity Score
Geography
Urban Hospitals
Teaching Hospitals
Cohort Studies
Retrospective Studies
Logistic Models
Databases

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Mannschreck, D., Matsuno, R. K., Moriarty, J. P., Borah, B. J., Dowdy, S. C., Tanner, E. J., ... Fader, A. N. (2016). Disparities in Surgical Care among Women with Endometrial Cancer. Obstetrics and Gynecology, 128(3), 526-534. https://doi.org/10.1097/AOG.0000000000001567

Disparities in Surgical Care among Women with Endometrial Cancer. / Mannschreck, Diana; Matsuno, Rayna K.; Moriarty, James P.; Borah, Bijan J; Dowdy, Sean Christopher; Tanner, Edward J.; Makary, Martin A.; Stone, Rebecca L.; Levinson, Kimberly L.; Temkin, Sarah M.; Fader, Amanda N.

In: Obstetrics and Gynecology, Vol. 128, No. 3, 01.09.2016, p. 526-534.

Research output: Contribution to journalArticle

Mannschreck, D, Matsuno, RK, Moriarty, JP, Borah, BJ, Dowdy, SC, Tanner, EJ, Makary, MA, Stone, RL, Levinson, KL, Temkin, SM & Fader, AN 2016, 'Disparities in Surgical Care among Women with Endometrial Cancer', Obstetrics and Gynecology, vol. 128, no. 3, pp. 526-534. https://doi.org/10.1097/AOG.0000000000001567
Mannschreck, Diana ; Matsuno, Rayna K. ; Moriarty, James P. ; Borah, Bijan J ; Dowdy, Sean Christopher ; Tanner, Edward J. ; Makary, Martin A. ; Stone, Rebecca L. ; Levinson, Kimberly L. ; Temkin, Sarah M. ; Fader, Amanda N. / Disparities in Surgical Care among Women with Endometrial Cancer. In: Obstetrics and Gynecology. 2016 ; Vol. 128, No. 3. pp. 526-534.
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AU - Dowdy, Sean Christopher

AU - Tanner, Edward J.

AU - Makary, Martin A.

AU - Stone, Rebecca L.

AU - Levinson, Kimberly L.

AU - Temkin, Sarah M.

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N2 - OBJECTIVE: To analyze contemporary U.S. use of minimally invasive surgery for the treatment of endometrial cancer and associated inpatient complications and costs. METHODS: In this retrospective cohort study, the National Inpatient Sample database was analyzed in patients with nonmetastatic endometrial cancer who underwent hysterectomy during 2012-2013. Hierarchical multiple logistic regression and propensity score matching were used to compare complications among patients treated with open compared with minimally invasive hysterectomy surgery. Cost of care was also compared using generalized linear modeling. RESULTS: We identified 9,799 patients; 52.4% underwent open and 47.6% minimally invasive hysterectomy. Many patients (43.4%) were treated at low-volume hospitals (less than 10 endometrial cancer cases annually). Patients were less likely to undergo open surgery in high-volume compared with low-volume hospitals (51.8% compared with 58.1%, respectively; adjusted odds ratio [OR] 0.35, 95% confidence interval [CI] 0.13-0.94) and more likely to undergo open surgery in rural compared with urban teaching hospitals (75.6% compared with 51.1%, respectively; adjusted OR 14.34, 95% CI 9.66-21.27), government compared with nonprofit hospitals (61.3% compared with 51.1%, respectively; adjusted OR 1.66, 95% CI 1.15-2.39), and in patients of black (67.9%; OR 1.46, 95% CI 1.30-1.65) and "other" race (60.5%; adjusted OR 2.39, 95% CI 1.99-2.87) compared with white race (49.2%, referent). Open surgery was associated with increased perioperative complications (adjusted OR 2.80, 95% CI 2.48-3.17) and a $1,243 increase in cost per case compared with minimally invasive approaches (P<.001). Using minimally invasive surgery for 80% of study patients may have averted 2,733 complications and saved approximately $19 million. CONCLUSION: Most U.S. women with endometrial cancer continue to be treated with open hysterectomy surgery despite increased complication rates and financial costs associated with this approach. A disparity in endometrial cancer surgical care exists that is affected by patient race and hospital geography and cancer volumes.

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