Abstract
In both the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT) and the Canadian Coronary Atherectomy Trial (CCAT), directional coronary atherectomy (DCA) achieved better initial angiographic results than did percutaneous transluminal coronary angioplasty (PTCA). However, DCA was associated with higher rates of periprocedural myocardial infarction and abrupt closure (at least in CAVEAT). Moreover, only in the prespecified subgroup of CAVEAT patients with lesions in the proximal left anterior descending artery were restenosis rates significantly lower in DCA-treated patients than in PTCA-treated patients. Since completion of these trials, there has been increasing emphasis on the need to achieve an ideal angiographic result to substantially decrease restenosis. Whether this strategy of more aggressive tissue removal by DCA and post-atherectomy dilatation to achieve an optimal result will decrease restenosis rates or increase complication rates is the subject of an ongoing randomized trial.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 97-100 |
| Number of pages | 4 |
| Journal | Journal of Myocardial Ischemia |
| Volume | 7 |
| Issue number | 2 |
| State | Published - Mar 28 1995 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Directional coronary atherectomy : Still in evolution. / Holmes, David; Garratt, K. N.
In: Journal of Myocardial Ischemia, Vol. 7, No. 2, 28.03.1995, p. 97-100.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Directional coronary atherectomy
T2 - Still in evolution
AU - Holmes, David
AU - Garratt, K. N.
PY - 1995/3/28
Y1 - 1995/3/28
N2 - In both the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT) and the Canadian Coronary Atherectomy Trial (CCAT), directional coronary atherectomy (DCA) achieved better initial angiographic results than did percutaneous transluminal coronary angioplasty (PTCA). However, DCA was associated with higher rates of periprocedural myocardial infarction and abrupt closure (at least in CAVEAT). Moreover, only in the prespecified subgroup of CAVEAT patients with lesions in the proximal left anterior descending artery were restenosis rates significantly lower in DCA-treated patients than in PTCA-treated patients. Since completion of these trials, there has been increasing emphasis on the need to achieve an ideal angiographic result to substantially decrease restenosis. Whether this strategy of more aggressive tissue removal by DCA and post-atherectomy dilatation to achieve an optimal result will decrease restenosis rates or increase complication rates is the subject of an ongoing randomized trial.
AB - In both the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT) and the Canadian Coronary Atherectomy Trial (CCAT), directional coronary atherectomy (DCA) achieved better initial angiographic results than did percutaneous transluminal coronary angioplasty (PTCA). However, DCA was associated with higher rates of periprocedural myocardial infarction and abrupt closure (at least in CAVEAT). Moreover, only in the prespecified subgroup of CAVEAT patients with lesions in the proximal left anterior descending artery were restenosis rates significantly lower in DCA-treated patients than in PTCA-treated patients. Since completion of these trials, there has been increasing emphasis on the need to achieve an ideal angiographic result to substantially decrease restenosis. Whether this strategy of more aggressive tissue removal by DCA and post-atherectomy dilatation to achieve an optimal result will decrease restenosis rates or increase complication rates is the subject of an ongoing randomized trial.
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UR - http://www.scopus.com/inward/citedby.url?scp=0028911551&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0028911551
VL - 7
SP - 97
EP - 100
JO - Journal of Myocardial Ischemia
JF - Journal of Myocardial Ischemia
SN - 1045-7984
IS - 2
ER -