Diltiazem-induced transient complete atrioventricular block in an elderly patient with acute on chronic renal failure

Jorge A. Brenes, Yong-Mei Cha

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Diltiazem is a calcium channel blocker commonly used in the treatment of various cardiovascular disorders such as hypertension, angina and supraventricular tachycardias. Metabolism occurs mainly in the liver, but a small percentage of unchanged drug and metabolites are excreted in the urine. Toxicity from this medication usually presents in the form of dysrrhytmias and heart block. Hence, we present a case of complete atrioventricular AV block in a patient receiving sustained- release diltiazem on a chronic basis. Risk factors such as advanced age and impaired renal function are discussed.

Original languageEnglish (US)
Pages (from-to)23-27
Number of pages5
JournalOpen Cardiovascular Medicine Journal
Volume7
Issue number1
DOIs
StatePublished - 2013

Fingerprint

Diltiazem
Atrioventricular Block
Chronic Kidney Failure
Supraventricular Tachycardia
Heart Block
Calcium Channel Blockers
Urine
Hypertension
Kidney
Liver
Pharmaceutical Preparations
Therapeutics

Keywords

  • AV block
  • Diltiazem
  • Renal failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

@article{07c6425ec0674128bd414a3c0bcfd158,
title = "Diltiazem-induced transient complete atrioventricular block in an elderly patient with acute on chronic renal failure",
abstract = "Diltiazem is a calcium channel blocker commonly used in the treatment of various cardiovascular disorders such as hypertension, angina and supraventricular tachycardias. Metabolism occurs mainly in the liver, but a small percentage of unchanged drug and metabolites are excreted in the urine. Toxicity from this medication usually presents in the form of dysrrhytmias and heart block. Hence, we present a case of complete atrioventricular AV block in a patient receiving sustained- release diltiazem on a chronic basis. Risk factors such as advanced age and impaired renal function are discussed.",
keywords = "AV block, Diltiazem, Renal failure",
author = "Brenes, {Jorge A.} and Yong-Mei Cha",
year = "2013",
doi = "10.2174/1874192401307010023",
language = "English (US)",
volume = "7",
pages = "23--27",
journal = "Open Cardiovascular Medicine Journal",
issn = "1874-1924",
publisher = "Bentham Science Publishers B.V.",
number = "1",

}

TY - JOUR

T1 - Diltiazem-induced transient complete atrioventricular block in an elderly patient with acute on chronic renal failure

AU - Brenes, Jorge A.

AU - Cha, Yong-Mei

PY - 2013

Y1 - 2013

N2 - Diltiazem is a calcium channel blocker commonly used in the treatment of various cardiovascular disorders such as hypertension, angina and supraventricular tachycardias. Metabolism occurs mainly in the liver, but a small percentage of unchanged drug and metabolites are excreted in the urine. Toxicity from this medication usually presents in the form of dysrrhytmias and heart block. Hence, we present a case of complete atrioventricular AV block in a patient receiving sustained- release diltiazem on a chronic basis. Risk factors such as advanced age and impaired renal function are discussed.

AB - Diltiazem is a calcium channel blocker commonly used in the treatment of various cardiovascular disorders such as hypertension, angina and supraventricular tachycardias. Metabolism occurs mainly in the liver, but a small percentage of unchanged drug and metabolites are excreted in the urine. Toxicity from this medication usually presents in the form of dysrrhytmias and heart block. Hence, we present a case of complete atrioventricular AV block in a patient receiving sustained- release diltiazem on a chronic basis. Risk factors such as advanced age and impaired renal function are discussed.

KW - AV block

KW - Diltiazem

KW - Renal failure

UR - http://www.scopus.com/inward/record.url?scp=84876096328&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876096328&partnerID=8YFLogxK

U2 - 10.2174/1874192401307010023

DO - 10.2174/1874192401307010023

M3 - Article

C2 - 23847692

AN - SCOPUS:84876096328

VL - 7

SP - 23

EP - 27

JO - Open Cardiovascular Medicine Journal

JF - Open Cardiovascular Medicine Journal

SN - 1874-1924

IS - 1

ER -