Dilation of esophageal strictures induced by radiation therapy for cancer of the esophagus

Santhi Swaroop Vege, D. C. Desai, K. M. Mohandas, V. Dhir, U. R. Dave, R. I. Gulla, K. A. Dinshaw, R. K. Deshpande, P. B. Desai

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

During a 2-year period, 103 consecutive patients undergoing dilation of esophageal strictures induced by radiation therapy for cancer of the esophagus were prospectively studied. The length of the strictures ranged from 0.5 to 13.5 cm (median, 5 cm) and the luminal diameter from 1 to 11 mm (median, 6 mm). Patients were referred for dilation from 2 weeks to 5 years (median, 2 months) after completion of radiation therapy. The guide wire was placed using fluoroscopy in 21 patients, endoscopy in 61, and a combination of endoscopy and fluoroscopy in 21. At least one dilator larger than the stricture could be passed in 101 (98%) patients. Five strictures were dilated to 16 mm, 29 to 15 mm, 28 to 14 mm, 16 to 12.8 mm, and 23 to 12 mm or less during the initial procedure. Development of complications and severe resistance were the limiting factors for optimal dilation. Relief of dysphagia was adequate in 66% of patients. The duration of dysphagia relief was 3 to 84 weeks (median, 16 weeks). Complications included persistent pain in 7 patients, unexplained fever in 2, perforation in 2, and delayed tracheo- esophageal fistula in 1. Two patients died of treatment related complications. Repeated dilation was required in 32 of the 75 patients on long-term follow-up. We conclude that adequate palliation of dysphagia can be achieved by dilation in two-thirds of patients with radiation therapy- induced strictures of the esophagus. Dilation of these strictures is relatively simple and safe if performed with care.

Original languageEnglish (US)
Pages (from-to)311-315
Number of pages5
JournalGastrointestinal Endoscopy
Volume40
Issue number3
StatePublished - 1994
Externally publishedYes

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Esophageal Stenosis
Esophageal Neoplasms
Dilatation
Radiotherapy
Pathologic Constriction
Deglutition Disorders
Fluoroscopy
Endoscopy
Tracheoesophageal Fistula
Esophagus
Fever
Pain

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Vege, S. S., Desai, D. C., Mohandas, K. M., Dhir, V., Dave, U. R., Gulla, R. I., ... Desai, P. B. (1994). Dilation of esophageal strictures induced by radiation therapy for cancer of the esophagus. Gastrointestinal Endoscopy, 40(3), 311-315.

Dilation of esophageal strictures induced by radiation therapy for cancer of the esophagus. / Vege, Santhi Swaroop; Desai, D. C.; Mohandas, K. M.; Dhir, V.; Dave, U. R.; Gulla, R. I.; Dinshaw, K. A.; Deshpande, R. K.; Desai, P. B.

In: Gastrointestinal Endoscopy, Vol. 40, No. 3, 1994, p. 311-315.

Research output: Contribution to journalArticle

Vege, SS, Desai, DC, Mohandas, KM, Dhir, V, Dave, UR, Gulla, RI, Dinshaw, KA, Deshpande, RK & Desai, PB 1994, 'Dilation of esophageal strictures induced by radiation therapy for cancer of the esophagus', Gastrointestinal Endoscopy, vol. 40, no. 3, pp. 311-315.
Vege, Santhi Swaroop ; Desai, D. C. ; Mohandas, K. M. ; Dhir, V. ; Dave, U. R. ; Gulla, R. I. ; Dinshaw, K. A. ; Deshpande, R. K. ; Desai, P. B. / Dilation of esophageal strictures induced by radiation therapy for cancer of the esophagus. In: Gastrointestinal Endoscopy. 1994 ; Vol. 40, No. 3. pp. 311-315.
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