Diffuse pulmonary lymphangiomatosis: CT findings

S. J. Swensen, T. E. Hartman, J. R. Mayo, T. V. Colby, H. D. Tazelaar, N. L. Muller

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Objective: Our objective was to determine and report the CT findings in patients with diffuse pulmonary lymphangiomatosis (DPL). Materials and Methods: We retrospectively reviewed the CT findings in eight patients with pathologically proven DPL. The patients ranged in age: from 3 to 35 years (mean 15 years) and included four male and four female patients. The CT scans were analyzed for type of pulmonary infiltrative process and its distribution, presence or absence of pleural fluid or thickening, and presence or absence of thoracic lymphadenopathy. Results: The main abnormality seen on conventional and high resolution CT in all patients was smooth thickening of the interlobular septa and bronchovascular bundles. Seven of eight patients had patchy bilateral areas of ground-glass attenuation. All eight patients had diffuse increased attenuation of the mediastinal fat, approximating that of water, and mild bilateral perihilar infiltration. Seven of the eight had bilateral pleural effusions or smooth thickening of the pleura (or both), and two had regions of calcified pleural thickening. Conclusion: The constellation of CT features of DPL is distinctive and includes diffuse, smooth thickening of interlobular sepia and bronchovascular bundles with extensive infiltration of the mediastinal fat and associated perihilar infiltration. Since the CT findings described are suggestive but not pathognomonic, definitive diagnosis requires lung biopsy.

Original languageEnglish (US)
Pages (from-to)348-352
Number of pages5
JournalJournal of Computer Assisted Tomography
Volume19
Issue number3
StatePublished - 1995

Fingerprint

Fats
Sepia
Lung
Pleura
Pleural Effusion
Lymphangiectasia pulmonary congenital
Glass
Thorax
Biopsy
Water
Lymphadenopathy

Keywords

  • Computed tomography
  • Lungs, diseases
  • Lymphangiomatosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Swensen, S. J., Hartman, T. E., Mayo, J. R., Colby, T. V., Tazelaar, H. D., & Muller, N. L. (1995). Diffuse pulmonary lymphangiomatosis: CT findings. Journal of Computer Assisted Tomography, 19(3), 348-352.

Diffuse pulmonary lymphangiomatosis : CT findings. / Swensen, S. J.; Hartman, T. E.; Mayo, J. R.; Colby, T. V.; Tazelaar, H. D.; Muller, N. L.

In: Journal of Computer Assisted Tomography, Vol. 19, No. 3, 1995, p. 348-352.

Research output: Contribution to journalArticle

Swensen, SJ, Hartman, TE, Mayo, JR, Colby, TV, Tazelaar, HD & Muller, NL 1995, 'Diffuse pulmonary lymphangiomatosis: CT findings', Journal of Computer Assisted Tomography, vol. 19, no. 3, pp. 348-352.
Swensen SJ, Hartman TE, Mayo JR, Colby TV, Tazelaar HD, Muller NL. Diffuse pulmonary lymphangiomatosis: CT findings. Journal of Computer Assisted Tomography. 1995;19(3):348-352.
Swensen, S. J. ; Hartman, T. E. ; Mayo, J. R. ; Colby, T. V. ; Tazelaar, H. D. ; Muller, N. L. / Diffuse pulmonary lymphangiomatosis : CT findings. In: Journal of Computer Assisted Tomography. 1995 ; Vol. 19, No. 3. pp. 348-352.
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