Diffuse placoid choroidopathy in a patient with common variable immunodeficiency

Colin A. McCannel, Jose S. Pulido

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Unilateral diffuse placoid choroidopathy can be seen in the setting of common variable immunodeficiency (CVID). A 55-year-old woman with a 20-year history of CVID presented with multiple hypopigmented placoid lesions in the right eye. Diffuse lymphadenopathy led to lymph node biopsies (mediastinal and axillary) and angiotensin-converting enzyme and serum calcium level determination, which were all normal. CVID, the most common type of significant hypogammaglobulinemia, may be associated with a placoid choroidopathy. The cause of this CVID choroidopathy is unclear at this time, but may be secondary to lymphoid hyperplasia or granulomatous disease.

Original languageEnglish (US)
Pages (from-to)84-86
Number of pages3
JournalInternational archives of allergy and immunology
Volume147
Issue number1
DOIs
StatePublished - Aug 1 2008

Keywords

  • Choroidal granuloma
  • Common variable immunodeficiency
  • Hypogammaglobulinemia
  • Placoid choroidopathy
  • Sarcoidosis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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