Diffuse lung disease: Diagnostic accuracy of CT in patients undergoing surgical biopsy of the lung

Stephen J. Swensen, Gregory L. Aughenbaugh, Jeffrey L. Myers

Research output: Contribution to journalArticle

148 Scopus citations

Abstract

PURPOSE: To determine if there is a subset of patients undergoing surgical biopsy for diffuse lung disease in whom accurate diagnosis can be made with computed tomography (CT) only. MATERIALS AND METHODS: Two chest radiologists retrospectively reviewed the CT scans of 85 patients in whom surgical biopsy for diffuse lung disease was performed. Thin-section CT images were available in 58 (68%) of the 85 cases. By consensus, the radiologists listed the three most likely diagnoses in order of probability and rated their level of confidence in the first choice. RESULTS: Each of 85 patients with diffuse lung disease had one of 16 diseases. In 79 (93%) cases, the correct diagnosis was one of the three choices. In 54 (64%) cases, the correct diagnosis was the radiologists' first choice. A high level of confidence in the first choice was reached in 20 (24%) cases; all 20 cases were forms of chronic lung disease. In 18 (90%) of these 20 cases, the first choice was correct. CONCLUSION: In a subset of patients with diffuse lung disease who undergo surgical biopsy, accurate diagnosis can be made with CT findings only.

Original languageEnglish (US)
Pages (from-to)229-234
Number of pages6
JournalRadiology
Volume205
Issue number1
DOIs
StatePublished - Oct 1997

Keywords

  • Computed tomography (CT), thin section
  • Lung, bronchiolitis obliterans
  • Lung, diseases
  • Lung, fibrosis
  • Lung, infection
  • Lung, interstitial disease
  • Lung, lymphoma/leukemia
  • Pneumonitis, hypersensitivity

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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