Differentiation of Constriction and Restriction: Complex Cardiovascular Hemodynamics

Jeffrey B. Geske, Nandan S. Anavekar, Rick A. Nishimura, Jae Kuen Oh, Bernard J. Gersh

Research output: Contribution to journalReview article

18 Scopus citations

Abstract

Differentiation of constrictive pericarditis (CP) from restrictive cardiomyopathy (RCM) is a complex and often challenging process. Because CP is a potentially curable cause of heart failure and therapeutic options for RCM are limited, distinction of these 2 conditions is critical. Although different in regard to etiology, prognosis, and treatment, CP and RCM share a common clinical presentation of predominantly right-sided heart failure, in the absence of significant left ventricular systolic dysfunction or valve disease, due to impaired ventricular diastolic filling. Fundamental to the diagnosis of either condition is a clear understanding of the underlying hemodynamic principles and pathophysiology. We present a contemporary review of the pathophysiology, hemodynamics, diagnostic assessment, and therapeutic approach to patients presenting with CP and RCM.

Original languageEnglish (US)
Pages (from-to)2329-2347
Number of pages19
JournalJournal of the American College of Cardiology
Volume68
Issue number21
DOIs
StatePublished - Nov 29 2016

Keywords

  • constrictive pericarditis
  • heart failure
  • hemodynamics
  • restrictive cardiomyopathy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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