Differentiation of chronic lymphocytic leukemia from Hodgkin's disease using immunologic marker studies

T. V. Colby, R. A. Warnke, J. S. Burke, R. F. Dorfman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Four consecutive lymph node biopsies from one patient showed features typical of lymphocyte-predominant Hodgkin's disease. When the patient developed lymphocytosis of the peripheral blood and a staging bone marrow biopsy was found to have nodular lymphoid infiltrates atypical for Hodgkin's disease, the fourth node biopsy was performed in order to perform immunologic marker studies. A monoclonal cell population was identified and the lymph nodes were interpreted as chronic lymphocytic leukemia mimicking lymphocyte-predominant Hodgkin's disease. The diagnostic usefulness of immunologic marker studies is stressed.

Original languageEnglish (US)
Pages (from-to)707-710
Number of pages4
JournalAmerican Journal of Surgical Pathology
Volume5
Issue number7
StatePublished - 1981
Externally publishedYes

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B-Cell Chronic Lymphocytic Leukemia
Hodgkin Disease
Biomarkers
Biopsy
Lymph Nodes
Lymphocytes
Lymphocytosis
Bone Marrow
Population

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine

Cite this

Differentiation of chronic lymphocytic leukemia from Hodgkin's disease using immunologic marker studies. / Colby, T. V.; Warnke, R. A.; Burke, J. S.; Dorfman, R. F.

In: American Journal of Surgical Pathology, Vol. 5, No. 7, 1981, p. 707-710.

Research output: Contribution to journalArticle

Colby, T. V. ; Warnke, R. A. ; Burke, J. S. ; Dorfman, R. F. / Differentiation of chronic lymphocytic leukemia from Hodgkin's disease using immunologic marker studies. In: American Journal of Surgical Pathology. 1981 ; Vol. 5, No. 7. pp. 707-710.
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