Differentiation of chronic lymphocytic leukemia from Hodgkin's disease using immunologic marker studies

T. V. Colby, R. A. Warnke, J. S. Burke, R. F. Dorfman

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Four consecutive lymph node biopsies from one patient showed features typical of lymphocyte-predominant Hodgkin's disease. When the patient developed lymphocytosis of the peripheral blood and a staging bone marrow biopsy was found to have nodular lymphoid infiltrates atypical for Hodgkin's disease, the fourth node biopsy was performed in order to perform immunologic marker studies. A monoclonal cell population was identified and the lymph nodes were interpreted as chronic lymphocytic leukemia mimicking lymphocyte-predominant Hodgkin's disease. The diagnostic usefulness of immunologic marker studies is stressed.

Original languageEnglish (US)
Pages (from-to)707-710
Number of pages4
JournalAmerican Journal of Surgical Pathology
Volume5
Issue number7
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine

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